LOCUS       NZ_CP115183            23597 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Clostridioides difficile R20291 chromosome, complete genome.
ACCESSION   NZ_CP115183
VERSION     NZ_CP115183.1
KEYWORDS    .
SOURCE      Clostridioides difficile R20291 (Clostridium difficile R20291)
  ORGANISM  Clostridioides difficile R20291
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP115183.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
            ##gutSMASH-Data-START##
            Version      :: 2.0.0-75c9ef8(changed)
            Run date     :: 2024-12-20 13:41:33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3213098
            Orig. end    :: 3236695
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23597
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3223098:3226695]"
                     /cutoff="5000"
                     /detection_rule="(BilR_short and Flavodoxin_3)"
                     /neighbourhood="10000"
                     /product="Bilirubin_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13597
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(BilR_short and Flavodoxin_3)"
                     /neighbourhood="10000"
                     /product="Bilirubin_reductase"
                     /protocluster_number="1"
     cand_cluster    1..23597
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(BilR_short and Flavodoxin_3)"
                     /kind="single"
                     /product="Bilirubin_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23597
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Bilirubin_reductase"
                     /region_number="17"
                     /rules="(BilR_short and Flavodoxin_3)"
                     /tool="gutsmash"
     misc_feature    403..421
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 27.45"
                     /tool="gutsmash"
     misc_feature    787..800
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.42"
                     /tool="gutsmash"
     gene            complement(964..1257)
                     /locus_tag="O9S30_RS14780"
                     /old_locus_tag="O9S30_14780"
     CDS             complement(964..1257)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /locus_tag="O9S30_RS14780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14780"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_009893732.1"
                     /transl_table=11
                     /translation="MGQLENVKYTNLEPKKLIEQIGKKKDKKDIWIVGGGDIVKLFMKD
                     NLIDDYYIYILPIILGRGISLFKSGIDKTNLNFKKVSNIGELVKLEYSKKQK"
     gene            complement(1226..1510)
                     /locus_tag="O9S30_RS14785"
                     /old_locus_tag="O9S30_14785"
     CDS             complement(1226..1510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891095.1"
                     /locus_tag="O9S30_RS14785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14785"
                     /product="hypothetical protein"
                     /protein_id="WP_009891095.1"
                     /transl_table=11
                     /translation="MRKVVLYIATSLDGYIAEENGSVSFLDEISSEFKNEQEDDYNTFY
                     DTIDTIIMGNSTYVQIANELSPNEWYYKGKECYIYSNTINGTTGECKVY"
     gene            1817..2929
                     /locus_tag="O9S30_RS14790"
                     /old_locus_tag="O9S30_14790"
     CDS             1817..2929
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /locus_tag="O9S30_RS14790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14790"
                     /product="alanine racemase"
                     /protein_id="WP_003426625.1"
                     /sec_met_domain="Ala_racemase_N (E-value: 7.8e-30,
                     bitscore: 101.9, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHKS
                     TYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKINLI
                     CATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENIKIV
                     GISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVEAEAA
                     SKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSKCLGLD
                     KGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNHSCSTAN
                     LTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(3112..4008)
                     /locus_tag="O9S30_RS14795"
                     /old_locus_tag="O9S30_14795"
     CDS             complement(3112..4008)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /locus_tag="O9S30_RS14795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14795"
                     /product="IS3 family transposase"
                     /protein_id="WP_139142266.1"
                     /transl_table=11
                     /translation="MFKKVKYPIGQVKVSDKFKTIKLMSRKYSISSMCKLIGVSRSGYY
                     KWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDSPINHKKVYRL
                     MKELGIKSIIRKKVYRRKFKSYEVYDNILNREFRANQPLEKICMDITYIPIGKKFLYMN
                     VAKDLFNGEIVAYEISTKMDTKLVNKTVNQLINMNLAKDCILHTDQGSQYTSRSYSKRL
                     KDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYFYNNER
                     IQLKNGMSPIEYRTHSA"
     gene            complement(3966..4283)
                     /locus_tag="O9S30_RS14800"
                     /old_locus_tag="O9S30_14800"
     CDS             complement(3966..4283)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="O9S30_RS14800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14800"
                     /product="transposase"
                     /protein_id="WP_009891099.1"
                     /transl_table=11
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQNW
                     IKDYKNKGKTAFNEETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLDKS
                     K"
     misc_feature    4288..4304
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.5"
                     /tool="gutsmash"
     misc_feature    complement(4289..4304)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.37"
                     /tool="gutsmash"
     gene            complement(4600..5109)
                     /locus_tag="O9S30_RS14805"
                     /old_locus_tag="O9S30_14805"
     CDS             complement(4600..5109)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /locus_tag="O9S30_RS14805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14805"
                     /product="YjiG family protein"
                     /protein_id="WP_003426630.1"
                     /transl_table=11
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIMG
                     YVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQGL
                     ITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVRVLL
                     TVMGLM"
     gene            complement(5111..5758)
                     /locus_tag="O9S30_RS14810"
                     /old_locus_tag="O9S30_14810"
     CDS             complement(5111..5758)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /locus_tag="O9S30_RS14810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14810"
                     /product="nucleoside recognition domain-containing protein"
                     /protein_id="WP_003431751.1"
                     /transl_table=11
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANLT
                     GSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIFNP
                     LLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSAVIL
                     NTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(5772..6944)
                     /locus_tag="O9S30_RS14815"
                     /old_locus_tag="O9S30_14815"
     CDS             complement(5772..6944)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /locus_tag="O9S30_RS14815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14815"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_009891103.1"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.3e-24, bitscore:
                     84.9, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAER
                     LKLEFEKEGLDCELVDVGENGNTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPFKI
                     IEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGADVIL
                     REAKGALCAFNMETGLVDNSLCIGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEEMANK
                     ILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQVREIC
                     KETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSRENGFGELNAKRLGGSSDASY
                     LTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            7212..8588
                     /locus_tag="O9S30_RS14820"
                     /old_locus_tag="O9S30_14820"
     CDS             7212..8588
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /locus_tag="O9S30_RS14820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14820"
                     /product="hypothetical protein"
                     /protein_id="WP_009891106.1"
                     /transl_table=11
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNNL
                     PNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQKD
                     IDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIHLDL
                     LRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDKNKSA
                     TCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEIHTTKE
                     ILNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLNGNCTFI
                     VNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNSNNVSAEI
                     LADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFLNKMQKLNS
                     "
     gene            complement(8839..9672)
                     /locus_tag="O9S30_RS14825"
                     /old_locus_tag="O9S30_14825"
     CDS             complement(8839..9672)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /locus_tag="O9S30_RS14825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14825"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_009891108.1"
                     /transl_table=11
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENVE
                     DIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKMLES
                     DELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIAITV
                     FPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSDTIAD
                     YLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIVLLIIGVYKLFKKYN"
     gene            complement(10001..10366)
                     /locus_tag="O9S30_RS14830"
                     /old_locus_tag="O9S30_14830"
     CDS             complement(10001..10366)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Bilirubin_reductase: Flavodoxin_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024055.4"
                     /locus_tag="O9S30_RS14830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14830"
                     /product="flavodoxin"
                     /protein_id="WP_009901191.1"
                     /sec_met_domain="Flavodoxin_3 (E-value: 1.4e-38, bitscore:
                     130.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIE
                     SIIPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEI
                     YEASMFAKNMMIKASIV"
     gene            complement(10532..11650)
                     /gene="tnpB"
                     /locus_tag="O9S30_RS14835"
                     /old_locus_tag="O9S30_14835"
     CDS             complement(10532..11650)
                     /codon_start=1
                     /gene="tnpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /locus_tag="O9S30_RS14835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14835"
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_270178582.1"
                     /transl_table=11
                     /translation="MIEVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVYK
                     NDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKS
                     KKINRFSYKTNFTNGNIVYCGQHIKLPKLGMVKVRDKQVPKGRILNATISKEPSGRYYV
                     SLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSR
                     KTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKDNDIICIEDLQVKNMIRNRK
                     LSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREW
                     ICPSCNETHDRDINASINILKEGLRLITIQNK"
     misc_feature    11662..11671
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="gutsmash"
     gene            complement(12296..12415)
                     /locus_tag="O9S30_RS14840"
                     /old_locus_tag="O9S30_14840"
     CDS             complement(12296..12415)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Bilirubin_reductase: Flavodoxin_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024055.4"
                     /locus_tag="O9S30_RS14840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14840"
                     /product="flavodoxin family protein"
                     /protein_id="WP_009891112.1"
                     /sec_met_domain="Flavodoxin_3 (E-value: 1.4e-11, bitscore:
                     42.2, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLVLYSSLTGNTKKIAYAIYDEIQEEKDIKDVNELVD"
     gene            complement(12503..13597)
                     /gene="bilR"
                     /locus_tag="O9S30_RS14845"
                     /old_locus_tag="O9S30_14845"
     CDS             complement(12503..13597)
                     /codon_start=1
                     /gene="bilR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Bilirubin_reductase: BilR_short"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /locus_tag="O9S30_RS14845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14845"
                     /product="bilirubin reductase"
                     /protein_id="WP_009893735.1"
                     /sec_met_domain="BilR_short (E-value: 1.2e-151, bitscore:
                     502.5, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKSG
                     VALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVNLI
                     KDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMIQIH
                     GDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQENPH
                     YGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCFLYLAD
                     EVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDGRVDEIK
                     KCCYCNKKCADALQTRSQFGCILD"
     gene            complement(13599..14045)
                     /gene="bilQ"
                     /locus_tag="O9S30_RS14850"
                     /old_locus_tag="O9S30_14850"
     CDS             complement(13599..14045)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="bilQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MarR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891114.1"
                     /locus_tag="O9S30_RS14850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14850"
                     /product="bilirubin utilization transcriptional regulator
                     BilQ"
                     /protein_id="WP_009891114.1"
                     /sec_met_domain="MarR (E-value: 1.2e-11, bitscore: 42.1,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLIY
                     INKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGEEV
                     LGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEG"
     gene            14351..15541
                     /locus_tag="O9S30_RS14855"
                     /old_locus_tag="O9S30_14855"
     CDS             14351..15541
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /locus_tag="O9S30_RS14855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14855"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_003436139.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-52, bitscore:
                     177.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSV
                     EPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIMTC
                     GAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLDALK
                     NAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIY
                     DGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILG
                     FVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLFPKAPIE
                     DDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK"
     gene            15711..16673
                     /locus_tag="O9S30_RS14860"
                     /old_locus_tag="O9S30_14860"
     CDS             15711..16673
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /locus_tag="O9S30_RS14860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14860"
                     /product="DMT family transporter"
                     /protein_id="WP_009891115.1"
                     /transl_table=11
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGLV
                     LLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSCNP
                     VFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIFSMY
                     TVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHIFANIPIFS
                     GYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVLSPILALLILKEI
                     IPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(16791..17453)
                     /gene="zmp1"
                     /locus_tag="O9S30_RS14865"
                     /old_locus_tag="O9S30_14865"
     CDS             complement(16791..17453)
                     /codon_start=1
                     /gene="zmp1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /locus_tag="O9S30_RS14865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14865"
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="WP_009891116.1"
                     /transl_table=11
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAYSTTIQQNKDTLSQIVVFP
                     TGNYNKNEANAMVNRLANIDGKYLNVLKQDNLKIKLLSGKLTDEKEYAYLKGVVPKGWE
                     GTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSAQFK
                     QIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNLAK"
     regulatory      complement(17553..17638)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(17824..20778)
                     /locus_tag="O9S30_RS14870"
                     /old_locus_tag="O9S30_14870"
     CDS             complement(17824..20778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /locus_tag="O9S30_RS14870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14870"
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="WP_009893736.1"
                     /transl_table=11
                     /translation="MKKGNKKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGST
                     NSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEDNSTDNKKPEQTSEEDKSTDNKK
                     PEQTPEGEKPIDNKKPEQTPEGEKSIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNK
                     NTEKTPEEDNLLEDENLLKVLEEELNEDYGFVVKINNNTIETESMKKISFNLTYTPTSK
                     GIQAGDSITFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEA
                     YVKKVDEDTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGRKSTTV
                     FMPVKNKDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQ
                     SKNSISVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFD
                     RGDNYLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEDG
                     HDFRVVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESK
                     FFIAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSD
                     NQIVKYKINMSTYGVYDAGQVNLLDEVNPSLKISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAKK
                     VDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGVIQSSVKKPGIYYLVEVMAPSGYEK
                     LKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPVPPNTDEPIVNPPVPPSTDKPRK
                     PSNPSDTEDTIVINPPVPPSEDIINPPIPEILNPPVPPSEEVIETPVKQIVPIPEVVKP
                     SVSEEKNNKAKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLVVLRRNKNTN"
     misc_feature    20786..20802
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="gutsmash"
     regulatory      complement(20891..20976)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(21102..22280)
                     /locus_tag="O9S30_RS14875"
                     /old_locus_tag="O9S30_14875"
     CDS             complement(21102..22280)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /locus_tag="O9S30_RS14875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14875"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_009891122.1"
                     /transl_table=11
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVIK
                     VFIGMFTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSALIV
                     AFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIVSIMIKIWLSRFNKFVGNKIDSS
                     ALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKDTINP
                     LLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDIMEIHE
                     IIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHDFRIVGK
                     GSKKNLIFDIVVNPSEFSKDMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI"
     gene            22652..22837
                     /locus_tag="O9S30_RS14880"
                     /old_locus_tag="O9S30_14880"
     CDS             22652..22837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /locus_tag="O9S30_RS14880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_14880"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_009891124.1"
                     /transl_table=11
                     /translation="MFFISDIYTKSPIKFDTPLQKEVYKILQKLDIDFERVDTDEAITM
                     EDCVQINKKLNMKMVI"
     misc_feature    complement(23311..23331)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.67"
                     /tool="gutsmash"
     misc_feature    complement(23398..23412)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 17.58"
                     /tool="gutsmash"
ORIGIN
        1 tgagtaattg acataagctt aaatagtttc ttagaaacat tagcataata tgtatttgtt
       61 ttttcaaatc gctctgtttc ataatcatca tttccaaaag ctctaattac tcttattcca
      121 gttaaatttt ctctcgatat aaggtttaat ttatctagtc ctttttgttg ttttgaagat
      181 attgcctgag atacttttgc tattattgct actccaataa ttataaaagg tactgatata
      241 gccaatacta tagaaagttc cacacttgtt ctaattgtca ttattatact tatgatgaac
      301 ataactggag ttaataaggc agtccttagt agtatattaa caaattgttg aatttgaaat
      361 gcatcattcg ttgttcttgt aatcattgaa gaaattccaa atttattgta ttcagtatgt
      421 gaaaattctt gtgatttctc aaatatgtca tttcttatat ctctggttac acttgttgat
      481 accttagcag aacaataacc caacaatata ctacctacaa cccctataat agaaataata
      541 acaatcacta ttcccatttg ttttatgtaa gctatattct gatttgcaat accattgtca
      601 attattttag ctattatagt tggaatcccc aactcgacta atgcaaaact aaatatagcc
      661 agtatgttta atactattaa taacttataa ttctttaaat aacttaaaat taatttcata
      721 tttttctcct ttcttaattt ttgagatagt gtaatcatgt aataatacta aatttataaa
      781 tgcttaattt tataaaaaaa ggagaaaaga gttaacgcac tctcttctcc agcatattct
      841 ttttaataca ccctccgaca agtcgcttat atgttaacat atttgacaag taatgtcaat
      901 tcatatagct aaaagtcttt taaatgcttc atctcataac attgtaacaa attggcatgt
      961 aatttatttt tgttttttac tgtattccaa ttttacaagt tctccaatat tactaacttt
     1021 cttaaaattc aaattagtct tatctatacc agacttaaat agtgaaatcc ctctccccaa
     1081 tattattggc aatatatata tataataatc atcaattaag ttatctttca taaataattt
     1141 tactatatcg cctccaccaa ctatccaaat atctttttta tccttctttt ttccaatttg
     1201 ctcaattaat tttttaggtt ctaaattagt atactttaca ttctccagtt gtcccattaa
     1261 ttgtatttga gtatatatag cattccttac ccttatagta ccattcattt gggcttaatt
     1321 catttgcaat ctgtacatat gtggaatttc ccataatgat agtatcaatt gtatcgtaaa
     1381 aagtattata atcatcttcc tgctcattct taaattctga agatatctcg tctaaaaaac
     1441 ttacactgcc attctcttca gctatataac catctaaact tgtggcaata taaagtacta
     1501 cttttctcat gtttactacc tccaacattt atagtgtgat tattctatgt aaacatcact
     1561 tttttactca ttcaataata ccctattaat aaatcctcaa actaatttaa ataaactttg
     1621 cataaaacta aaaatatatt atataaataa tttaaaatca cactaactta ttgaaaattc
     1681 taattattac aaataaatat tgctctctgt taacgctagt tttataatat aattataagc
     1741 tattaatatt ataaagccga tattactaat ataataatta tagttaattt acttttgttg
     1801 aaaggtggta aataacatga aaatttcaga agtcgctact ccaaattttt tgctagattt
     1861 agaccagtta gaaaagaata tagataaaat tcaacaaatt tgtacaaata ataataaaca
     1921 actttggcct atgcttaaga cacataaaag tacttacata gcgagacttc aaaaaaatgc
     1981 aggtgctagt ggttttctag ttggaacact tgatgaaggt gaagctctga taaaagcagg
     2041 ttttgaagat attatgttgg cttatcctta catgggagaa gtaaatataa atagaattgt
     2101 gactatggca tcaaaaataa atttaatctg tgctacagat aatatagaat gtgctaaggc
     2161 ttatagtgaa gctttttcta aatcaaaaat agagtgcaag ctacttatta ttgtagattg
     2221 tggcttacac cgttttgggg ttgaaccaga aaaagtggtt gaacttgcta ctgaaatttc
     2281 taagctagaa aacatcaaga ttgttggtat aagttcgcat ccaggtcaag tgtacggttg
     2341 tagttctcca gaaggtgttc cagatgtttg tgttcaagaa gattcttcta tggagaaagc
     2401 atacaaagct ctaactgata atggatttaa tatagaaatt gtcgcttctg gtagtactcc
     2461 aacagttgaa gctgaagctg cttctaaaac tataactgct gtaagacctg gaaactatgt
     2521 atactatgat gctatacaga taggtttagg ttgtgctact gaagatatgt gtgctcttac
     2581 tgttgtgtgt actgtaatct caaaaaatag cagtggatat tatttaattg attgtggaag
     2641 taagtgcctt ggacttgata aaggtgcaca tggaaatagt agtattgttg gttatggtag
     2701 ggtatgtgga catccagaac ttactattga ttcactttca gaagaagttg gaaaaattaa
     2761 agtaaatggt gaaactgata taaaaattgg tgatagaata agaattatac ctaatcattc
     2821 ttgttccact gcaaacttga cgagtaattt attaggtttt agaggagata caatagaaaa
     2881 agtcatagaa gtagatattc gtgaaaattc aaaacaaatc atcctttaaa aatatattta
     2941 ttttgatatt aacatcatga aagtatattt ttcttaaaat tattgttaat aactaatgtt
     3001 aatgttggat aaataaaaaa cataaattct agaaatataa atttaaaaaa agaggctgtc
     3061 tcaaaattgg atatgtccct gtcaagtaga cagacttaaa aaaggctatc tttatgcgga
     3121 atgagttcga tattcaatcg gactcattcc attttttaat tgtattcttt cattattata
     3181 aaaataaata taatcattta ttagactaat catttccttt ggatctgtag tatcaattaa
     3241 atatattaat tcagatttaa aatgactgaa aaaactttct ataggagcat tatcccagca
     3301 gttgcccctt cgggacatag attgtataat accattatct ttaagccttt tagagtaaga
     3361 tctacttgta tattgtgaac cttgatctgt atgtaaaata caatctttag ctaaattcat
     3421 atttattagt tgatttactg ttttattaac taatttagta tccatttttg tacttatctc
     3481 atatgccact atttcaccat taaataaatc tttggctaca ttcatgtata agaatttttt
     3541 accgataggt atgtatgtta tatccataca aattttttct aatggttgat tagctctaaa
     3601 ttcacgattt aatatattat catatacctc atatgattta aacttacgtc tatatacttt
     3661 ctttctaata atagatttaa ttcctagttc tttcatcaac ctatatactt tcttatgatt
     3721 aatagggcta tcaagtattt tatttaaata agtacaaatt ctttttctac cgtaagttcc
     3781 tctatatttt ttatgtattt caattatata atccttaata attctatctt tgatacccct
     3841 atcggaagat tttttagaat aacttagcca tttatagtaa ccgcttcttg acacacctat
     3901 caacttacac atactagaaa tactatactt cctagacata agtttaattg ttttaaattt
     3961 atcgcttact ttgacttgtc caatagggta cttaactttt ttaaaaattc attctccatg
     4021 cgtaagtact tcaattcttc ttcaacagat ttaaattttc tattatcatt ttctagacta
     4081 atatttttaa atctgcctct agtttcctca ttaaatgcag ttttaccttt atttttataa
     4141 tcttttatcc agttttgaac ttgtgttttg cttcttatat tcagcatctc agcaattttg
     4201 tatgatgagt atccttcttt tatatataaa tttacagctt ttagtttaag ttctttgcta
     4261 tattttttat gttttttaga catagaaaaa cccccttaga gtatacgctt tttagactta
     4321 ttataatagc cttttattta aatgtctact ataaggggat tatactaaaa tagagataag
     4381 cctctctttc attgttgaaa ttatgaaaat atacttgatt taataccaaa agagtatctc
     4441 atgaactaaa aagttcattt tgagatactc tcttcttttt taattaatat acatattaat
     4501 tactatatta gtttattact atatatcaat tactattcat taattactat tcatcaattc
     4561 ttatatatca tttataatta ggttataatt ttatgttatt tacattaatc ccataacagt
     4621 gagtaaaact cttactatca acatccccac tattgcatca aatataggaa ctgccaacag
     4681 taacattcta tacttagtac tggcatttgc tacaagcact attctggcat aatgaccaac
     4741 tagagtaccc attaacatac atggcataat taatatggtt gcttgtggtg cagtgattag
     4801 accttgtgca aataagtttg cagctgtagc tgctcctgct gccttagcaa agaatgctgc
     4861 tatcaaaact acaacagatt ccccaggtag tccaaaaata cccattactg gaccaaaaat
     4921 atttcctaaa atatcaacta aaccagttaa ttgtaaaaac tgcactatta cataacccat
     4981 tatcatggct ggtaatatct gttcaacacc tatgtaaaaa cctttttttg ctccccccat
     5041 aaatatctca acagcagttt tcttaggttt actatttaca attgcatttc cagtattttg
     5101 ttgactcata ctacacagcc tccttagcct tattcttttt atttcttaca cctatgatta
     5161 atctaactag attagcacca agtattttac agaatatctc tataaggatt attggaccta
     5221 atgccaataa tgctattggt aaaagtggag cttgagtatt tattgtgttc agtataacag
     5281 ctgaaccagc atattgatat gctacaaata tagttctttc atcatctgtt atttccccac
     5341 tttcaaataa ttctttcgtc attattgagg ctacatctga actagtaaat gaagatacaa
     5401 atgctattcc tgctattcca ggtataccaa gcagaggtct aagtaatgga ttaaatatct
     5461 ttgatgctgc tttcattcct cccatagatt caactacatc tataagacct acagcaaaac
     5521 agacagttgg aatcaaagtc agagcaaata agaaaccatc ttttgctccc gttcctcctt
     5581 tacccataaa gtctacacca tctgcaatag taccaaatga acctgtcaga ttagcaaaat
     5641 ctaatgcttt aaggaagcct tgactatctt taaatactcc tgaaaataat actatcaata
     5701 caaataaaga taaataccct ttccatgtta ccttattatc tccagctgtt acatccatat
     5761 aaaatccccc tttatacctc aaatttatct aagtttaaaa taactgtaga aattaatttc
     5821 accctctcaa acatagaatc tactactgca tattctcttg atgtgtggtt ccattctcct
     5881 cttacaccaa atgaacagat tgtaggaacg tttgcaatag ttaaataact tgcatctgaa
     5941 ctacctccaa gtctcttagc atttaattct ccaaatccat tttctcttga cacttcattt
     6001 acaaatgtat gaaatctcat aacatcttct gtagtttcaa atggcatcat ttcacttata
     6061 aaattaactt ctgtagaagt tccttctatg taagtttctt tacatatctc tctaacttgt
     6121 tctttaacat tctccatttc ttctactttt tcaaatctaa ggtctacttt tatactacaa
     6181 tcttctggaa tagaattttc cactcttcca cccttaatca cacttacact tactgtagtt
     6241 ccaacatcta aattagtcaa tttttgtatg cgtagtatct tattagccat ttcttctata
     6301 gcatttcttc caccttcaaa atcattacct gcatgtgttt ctacaccttt tacatgtata
     6361 ttacatccta ttcttccttt tctacctata cataaactat tatctactaa tccagtttcc
     6421 atattaaaag cacaaagagc accttttgct tccctcaata taacatctgc accagttgaa
     6481 tctttatgac ctatctcttc atctccagaa aatactattt ttattggtct ttctttgtat
     6541 cctattttat ttaaagcttt aataacgtat aaagagatta ttataccccc cttcatatct
     6601 aaaacacctg ggccatatgc ttttccttct attattttaa atggattctc tccaaatgta
     6661 cctgtttcaa agacagtatc catgtgtcct gaaaaaatta tcggcttttt atctatatta
     6721 gaaccaagtg tacctatcaa tgtattacca ttttccccaa catctactag ttcacaatcc
     6781 aaaccttctt tttcaaattc aagctttaat ctctcagcta acttgtttac actttcttta
     6841 caatgtgtat aactttctat attaacaatc tctttccata atgaaactat ttcttctcta
     6901 ttctcatcaa caaacttaga aatttcattt aaatatgtat tcataatctt ctcctttatt
     6961 ttcaaataaa atgtatttct ttcctaaaat ctaagtttat tttaggaaat cttaaaagac
     7021 tagtccttaa ttacaaaata gcacaattat tcttgccagt caacatattt ttcagtcttt
     7081 tttatatttt ctgatttttc tttcaattat ccttttgtaa aataaattga cgcgttttat
     7141 ctactattat aaaatgaggt tataaattga ttgattagtt acaatactct cgaaatttta
     7201 aaggaggttt tatgaaatat aaaattggtt ttttgacaac atcttatttt atgtcagata
     7261 agtttaaaca agctcttaaa gaattaaatg atacttgtga aattacattt attgagctta
     7321 aaggggagaa tccttttaat aatttaccta atatatacta tgagcaagta gataattttg
     7381 atggatttgt atgcagtggt atagttccat atagtgaact tataataaat ataaaagaca
     7441 taaaagttcc attaaatttt ttaaagcttg atgaaagaga tttttataaa tacttattca
     7501 aattattaaa tagccaaaaa gatattgact ttacaaaatc atttatggat tttttaagag
     7561 aggacaacaa ttattatgat atatattcat taatagactc taataaatgt ccatatacaa
     7621 ttaaagattt taatatccct caacctgtat atgactttaa aaaattaaat gataaattat
     7681 tggaaataca tttagactta ttgcgagata ataagattaa cctttctttt actagaaatt
     7741 acatcattag ttgtgaactt aataagcttg gatatgattg tatttacatg gttccatcta
     7801 cagaatcaat cctgaataca tttaaatctc tggtgaatga aataacatta caaaacttag
     7861 acaaaaataa atctgcaact tgtatagtta cagtaaatag ttcagagtac ataaatgaag
     7921 atttgatatt taaaaatgat gagatacaaa atcaaatata taacactata ttaaattctc
     7981 tatcaagaca tggattctat ggagttcagg tcaaaaaaaa tgatatgaaa atagagatac
     8041 acactactaa agaaatatta aacaatatga ccaataacta tacagatttt tttatttcag
     8101 aagatttaaa agaaattaaa tatagcttaa atataggttg gggcattgga aatacaaata
     8161 ttcatgcaga gcaaaatgct cgtcaggcta atggtaaatc tgcttctttg aatggaaact
     8221 gtacttttat agtaaatgat actaatgata caataggccc tttatattca aataaaaatt
     8281 ctaataatat tgaagatagc tcaatagcca ataaagttgc ttcttttata cctctatcta
     8341 atacaaatgt atctaaaatc atgtgtatga ttaatgatag aaattcaaat aatgtgtcag
     8401 cagaaatatt agcagactat atgaacataa ctcttagaag tgctaataga atattgagta
     8461 tcttatataa agcaggaatt gcaactattg taaatacaaa actcgataat caaagaggaa
     8521 ggccaaaaaa aatatataaa gttgatttct tatcttttct aaataagatg cagaaattaa
     8581 attcttaata tttaattttt taataaaagc aatgtatttt ctctaatttt aaagaatcaa
     8641 aatgtttaaa ttttattaga atatacaact ttttacttta aaatacctaa accttttatc
     8701 agtgaaataa accataatat atcgtagctt attagaaaaa caaaataatt tcatatacaa
     8761 ataataaaat agccactaca atccataatt tgcagtggct actttttaca ctatcactta
     8821 ttacttaatt tttaaaaatt aattgtattt tttaaataat ttatacacac ctattatcag
     8881 taaaacaata aatacaagta tatctataaa aataattatt gtaacatgtc tggcaatatt
     8941 gtaaataaaa agtatagaga atatttctat agacaacgct acaaaacaca taaaattcgt
     9001 taaataatct gcaatagtat cactataaaa agcatgtatt tgtaaccatc tccatataaa
     9061 tggacgtaaa aggattctga atacaacaca aatgacaggg taggcataaa taaatttttt
     9121 atctacataa ttagctacac cattattcca ttggatagga atttgaggtg gcaactttgg
     9181 aaatactgtt attgcaatca acaaacaagc aatagtaata attccccagg taattttccc
     9241 tccccatata tataagaaac ttacagagtc aagtttaaaa acaggtttgt ttttattcca
     9301 gtattctggc aactcagtta tgtattgctc tactttcaaa ttcaaataac ttagctcatc
     9361 agattctaac attttattac acatagtttt tgcattttct aagtctgata ttttagtttc
     9421 gagaactttc tcctgtttct ctacaacttc aactaaagat actttctgta atataatatt
     9481 acggatatca tcaatagtaa ttcctagtgt acgtaaatat gcaatttttt tgatgtcctc
     9541 tacattttca tctgaatatt ctctatagcc attacgctca ttacgaaggg gtttaattaa
     9601 attctcgttc tcataaaaac gaatattaga gcgtgtcaat cctgtttttt cttcaacttc
     9661 tttaattgtc attttaaaca ctacctctct attctattaa tttacaacta taatatagtc
     9721 ttaaatattt tcactctata aaattgtata tttagtatat cttaaaatca agttaattat
     9781 cttttataaa ttttcataca ataatatctc ctttcaataa tatctctttt tctatattta
     9841 aaactatctt attttctata aaataatgta taaacaaggt ttacagtcaa gtatttttat
     9901 tatttttttg atttcataaa aaaaagcata gcaaatcatt tgctatactt ttttactaaa
     9961 ttatttattc tatatcttat atgaacttat tgtttaacta ctacacaata ctagctttaa
    10021 tcatcatatt ttttgcaaac atactggctt catatatttc ttgttcatct ggatgacttt
    10081 gagattcctc atggttattt aattgttggc gaatatgttc gttgtcagga gaaagtttta
    10141 acatctcttt atattttgct ttcaatcctt ctgctatctt accttgacat atgaatgaac
    10201 ctaatatttc attatctttt gggataattg attctatctt ttctattata ctagctccat
    10261 aacttccttt tttacttgct cccattgttc caaatagtgc tatcttttta ttgtgaatat
    10321 tttcaagcac ttgttttgaa tttttatcac aaattccctt gtccacccaa tagcctaaga
    10381 atactatatc ataattttca tagtcaatac catactgaac ctcccatgac taaagtcaca
    10441 gggttcctgc ttcatagaat tttgcatact aaaatatgtc ttactaattc tccacaggct
    10501 atccccgtag ttcctacggt tcttacataa gttatttatt ttgaattgtt attagtctta
    10561 atccttcttt taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac
    10621 taggacaaat ccattctctt atatttaaat ccttaacttc ctcgttttta tacccacatt
    10681 tattgcatat ttgtgaactt gcaaagaatt tacctacctt tacaatttgt ctaccatacc
    10741 aattagcctt gtattctaat tgacgaataa attctgacca tgacacatca gaaattaagc
    10801 gagatagttt acgatttcta atcatattct ttacttgtaa atcttctatg caaataatat
    10861 cgttatcttt tattagttta gtagatagtt tttgtagaaa atcatttctt tgattagcta
    10921 tatgttcttg aagtcttgca acttttaatc ttgctttatt tctatttaaa ctaccgattg
    10981 tttttctcga taattctctt tgtaatttag caagtttgtt taatgacttc ttaagatact
    11041 taggattttc tataaattct ccacaacttg agatacaaaa ttctttaatt cctaaatcta
    11101 aacctatctg attgttagta ttttcaaatg cttcaatatc tacatcagta cagcataatg
    11161 atacataata tctaccactt ggttctttag atatagtagc attaagtatt ctccctttag
    11221 gtacttgttt atcccttact ttaaccatac caagtttagg taattttata tgttgaccac
    11281 aatacacgat atttccattt gtaaagttag ttttatatga aaatctatta attttctttg
    11341 atttaaattt aggaaatcct gctttttctt taaagaattt tttatatgca ttatctaaat
    11401 cttttaaggc gttttgtagt gaaaatttgt caggttcctt aagccatttt aattcttttt
    11461 ttaaattggt caaatcagaa ctacactgtt tataagtaaa agtttcttta tcgtttttat
    11521 aaacttctat tcttttagca agatacttat tatatacaaa tctacaacat ccaaaagttt
    11581 tgttaattaa ctcttgttgt tttttatttg gatacattct aaacttataa gcttttttca
    11641 cttctatcac ctcacgttaa ttgttttttg atacactttt taatgatttt atcatattta
    11701 atatattata taatgctgtg gtgaacaatt tattaatcac ctatcataat attaacaaat
    11761 gtaattattt aaaacaatta tttagaaggt tttatattta attttaaata acatatttaa
    11821 gaaccgtaag tcttaacttt tatcattttt gaggttgtcg ttcacataag ttcgctacta
    11881 cctatgcagt tctcttatga acttcttaca ctttcatgca agcacagact atatcttatc
    11941 cttcggcatt atccgttaag gtctacccac ttccactacc gataacttgt agtgtacttc
    12001 cctcaagagg aatagtcgtt gaagtttctc ctattcggag tttacctgct gattgcccat
    12061 tttaaagtac ttaggattta accttatacc atctaaccaa ttttttctac tttcgtaact
    12121 ttcacactta ggtttatttc atccttatgt tttagtttgg ttagctttag gggtttccag
    12181 caattcaagt agtattggat aggttctatc ctatctctac atataggttt ccctatatgc
    12241 tgactatttt agctactaac tcatgactaa agtcacaagt gtgcgtagct attttttaat
    12301 caactaattc atttacatct ttaatgtctt tttcttcttg aatttcatca tatatagcat
    12361 aagcaatctt tttagtattt ccagttaaac ttgaatataa aactaaactt ttcatgatgt
    12421 ctcctcctct ttatctaaat acttatctaa atcaccaaaa atatattaac cttaacaaat
    12481 tatttatttt tataaagata ttctaatcta gtatacatcc aaactgagag cgtgtttgta
    12541 aagcatctgc acacttctta ttacaataac agcacttttt aatctcatct actcttccat
    12601 cttttacttt ctgtaaccaa ttactatctg ctagtaattg tcttgacata gaaaccatat
    12661 ctactctatt atttgaaata atactttcta taaaatctgg gctagacaat tttccaaccc
    12721 cacatactgg aagatttgtg tgtttcttta cttcatcagc taaatataaa aaacagcctt
    12781 catctttaaa gtaaggatga ttattggttg gtatagtatc ttctaatttt gaatgatttg
    12841 caagtgttac atgaaaactg tttacaccta gggattcaaa ttttttaaca aaatactcaa
    12901 cttccgaaag taaaactcct gcatttccat aatgaggatt ttcttgtctt attgcaaatt
    12961 tatagtctat tggaatgtcc ttaacttcat ctcggatact actaattatt tcgcttgcaa
    13021 atctacttct attatcacac gttccaccat attcatcatt tctattatta aatatacttg
    13081 atgaaaaact tcctacaagc ctatcaccat gaatttgaat catgtcaaaa cctgcttttt
    13141 ttgcattcaa tgctgttact ttaaataaat ttataatatt tttaatttct tctttgggca
    13201 tatttgttat gtaatctttt actccgtcat tcattatttt ttttatctca tcatgtgaag
    13261 taattcccat cttcatagta tctttaatta aattaacatc ataatctgaa caaaatagtt
    13321 gtgctgatac ctttgcacca gaattgtgta tttcatctac aattttcttg tatttaatga
    13381 ctccatcttc atccgatagg cttatagcta ccttatgaaa actaggtcta atagatacat
    13441 ctcctagagt aatcagagct actcctgact tagcaatatc agaaaacttt ttaatttttt
    13501 cttccaattt aagacccatg cttgtaggtg caaaagatac tctatttttt aattccaaat
    13561 ttccaatttt aattggtttt aataaattac aatacatcct atccttcctc cacagctgtt
    13621 tttatatcct ttaccacatg taaattcttt accagttctt tatattctgt atctgagaac
    13681 tcttttttta tgtggttatc ccactttgaa aatatgtttt ttatatcccc taatacttcc
    13741 tcacccttat ctgttactct caactgaaaa gctctactat cattagggtt ttggattttt
    13801 tctatgtatc catcttgttc taacctagat atagttcttg ttgtatgagc tttatcaact
    13861 tcaaattctg tagaaacatc attcaaagaa caattcctat ttttattaat ataaattaaa
    13921 tagaaatata gaccattcgt aagtttatat ggttttaaac atttttcaca ataaagttta
    13981 aagttttttt gcaagttaca aataatatat gacaaacttt catactgtaa atttttaaaa
    14041 tccatcttaa atttcccttc tataattata atatgtttga ctatatcaac tatattatat
    14101 taaacaatta atatagtcaa gaatatttta ttctctaaat ctatgtttta ttaattcttt
    14161 aaaaaactat tatataaaat aatcatgata aaattagaaa ttggaatttt taatatgcac
    14221 tgtacataaa tatattttat ataaaagttt atattttcaa acaagtaatt tttcgaaaat
    14281 tgtctaaatt cagtaaaaat atggtaatat atacataagc aatataaatc tataaaaagg
    14341 agtgttacat atgatatcta ataaaatgca aactttagtt gcaaatagtt ctgttataag
    14401 agctatgttt gaagaaggaa agaaactttc tgatatttat ggtgaggaaa atgtttttga
    14461 ttttagtata ggaaatccaa gtgttgaacc tccagagact attaaagcag ttataaatga
    14521 tattttaaat gaagaatctc caaatttagt tcatggatat atgaacaact caggatatga
    14581 ggatgtaaga gatgctattg ctgaacatat aaataaaaaa gatggattaa atcttacaag
    14641 agaaaattta attatgactt gtggtgctgc tggtggtcta aatattattt taaaaactct
    14701 tttaaatcct ggtgatgaag ttattgcttt tgcaccgtat tttggtgagt ataaaaatta
    14761 tacagaaaac tatgatggaa aattaataga agttcctaca aatatagaga cttttgaacc
    14821 agatttagat gctctaaaaa atgctattac tccaaaaaca agagctttaa taataaacac
    14881 tccaaataat cctactggtg tcatatattc tgaagaatta ttaaaaaatc ttggagaatt
    14941 attggattca aaacaaaaag aatttaatac aagcatatat ctaatttctg atgagccata
    15001 tagagaaata atttatgatg gtgccaaagt tccttgtgta ctaaaatact atagaaattc
    15061 atttataggg tactcttata gtaaatcatt atctctacct ggtgaacgta taggatatat
    15121 tgttgctaat gggcaaatgg atgattttga tgatgttatg tcttcattaa atgttgcaaa
    15181 tagaatactt ggatttgtaa atgctccttc tctttttcaa agggttattg caagaagttt
    15241 agatgcagaa gttgatgtaa atatttataa aaagaatttt gaccttctat ataatagttt
    15301 aatcgatatg ggatattctt gtgttaaacc taatggtaca ttctatttgt tcccaaaagc
    15361 tccaattgaa gatgataaaa aattctgcaa tgatgcaaaa caatttaatt tattattagt
    15421 accaggttct tcttttggtt gtccaggtca ttttagagta tcatattgtg tatcttatga
    15481 taaagttaaa agttctttac cagcatttga aaaattagcc aaattatata atttaaaata
    15541 actaaatcaa agtaattcaa ataattaact accttagtat agaatactta cattctatat
    15601 taaggtagtt tataatttta tgtactatat tttatacata ccatattatt ccaatatgct
    15661 tgaatattct tatctatagt actaatataa attacaagga ggtgtttgac ttgaaaaaag
    15721 gttatgttta tataatactg actaccttat tttttagttc aatggaaatt agtctaaaaa
    15781 ctgtcactaa tgactttaat cccttacaaa taactttatc aagatttttt gttggcggtt
    15841 tagtcttact accttttgct gtaaaaagat taagagctct tagtctttct attacaaaat
    15901 cagacttaaa atactttgca tttttaggtt ttatgtgtgt agtagtaagt atgtcattgt
    15961 atcaactggc tgttctaaac acaaaggcat ctgtagttgc tgttttgttc agttgtaatc
    16021 cagtctttgt aatgctttta gcttacttaa ttttgaagga aaaaatatat aggcacaatg
    16081 taatttcact tatattagaa gttcttggaa ttatagttat aataaatcca ttgcatacaa
    16141 aactaactct tagtggaata ttcttaacat tatcttctgc tattattttt tcaatgtata
    16201 ctgtatttgg taaaagaaaa accttaaaat ttggtggaat agttgtaact tgctttagct
    16261 ttatatttgg tagtttggaa atgttgatat tggttttact cactaaaatt aattttatcg
    16321 cagatatatt aaataaaaat aaacttcata tatttgcaaa tatccctatt tttagtggat
    16381 ataccttaca caatatgccc attatgattt atgtattcgt atttgttaca ggtgttggtt
    16441 atgcacttta ctttatggca atggaagcta catctactag tcttacatct ttagtattct
    16501 tctttaaacc agtactatct ccaatactag cattattaat acttaaagaa attatcccta
    16561 taaacatggt tataggaatt ttattgatag taattggttc aataatttct attataccta
    16621 cgataattac tcaaatgcat aataaacacg ttgaagcctt gtataaggag tagtaattga
    16681 taatctatca agttatacat aagacaaaat ttattagatt taaacgcaat ataaaagaga
    16741 tgctattata atagcatctc ttttatattt attttaaatt tattaaagct ctatttagct
    16801 aggttttgca aaaagctata agtttgtgga caagctgatt ttaacttact atttgtatct
    16861 tgatttaaat agtaatatgc aaatgcttct gcaaaaaatt cttctggata tacacctaag
    16921 tagtttacat tacctaaaga acgaccttct ttagcaaata tttgtttgaa ttgtgctgat
    16981 ttagatatat catttaatac tatatggtct attgcatgtg ctgtttcatg taattctaaa
    17041 tttattgcat catgcccttt acctttgtta ctaaatccta ttctaagagc tactgtactt
    17101 ccacctaagc ctggaacatc atcccaagtt tttccagtac cttcccatcc cttaggaact
    17161 acacctttta aataagcata ttctttttca tctgttaact ttccacttaa taattttatt
    17221 tttaagttat cttgctttaa tacatttaaa tactttccat ctatattagc taatctattt
    17281 accatagcat tagcttcgtt tttattgtaa tttccagttg gaaaaactac tatttgacta
    17341 agtgtgtctt tattttgttg tatagtagta ctatatgcat gtgcacttac tggaactgaa
    17401 cttattaaga atattgatat tatagctatt aataattttt tacttggtct catattattc
    17461 cctcctttga gttaggccgg gagtaataaa tttcaaaata aaaaagatac ccaagagtat
    17521 ctttgtatat acaaaaagaa atttttactc ttttcggcaa ctggctggca tggtttacta
    17581 aactttagcc cctatagctt tgcgtgacta ggtttcccta gttttgcctc atttaatttt
    17641 atatctatat tatagcttat atctttttaa ttgtctatat ccctttggaa cttttttcta
    17701 aaaagttatt atttttttac ataaatcttc aaaaaaaaat atcttctaac aatattttca
    17761 ttattaaata ttgttttaga agatattttt taatataact tatatttttt ataatgttag
    17821 ggtctaattt gtatttttat ttcttcttaa tacgacaagt cctacaatag ctcctataac
    17881 taaaagtatt tctccaataa ttgtagtact atcccctgtt tttggtggta ctggtggatt
    17941 taccaaagta tcatctttag ctttattatt tttttcttct gacactgatg gctttaccac
    18001 ttctggtatt ggaacaatct gtttaacagg agtttctatc acctcttctg atggtggtac
    18061 tggtggattc aatatctctg gtattggagg atttattata tcttctgacg gtggtactgg
    18121 tggatttata actatagtat cctctgtatc agatggattt gatggtttcc ttggtttatc
    18181 tgtgcttggt ggcactggtg gatttactat tggttcatct gtatttggcg gtacaggtgg
    18241 atttactggt ggattttctt gtcttatgtt ttctatattt ccgatatcta ctattctacc
    18301 aatatcttta ttaccaattt caaccttaat tttatccttc agtttttcat atccacttgg
    18361 agccatcact tctactaaat aatatattcc tggttttttt acactagatt gaattacacc
    18421 atcttcatca ctaactaaat ccttaactac tatatttcca aatgcatctt ctaaattgaa
    18481 cttagcacct gaaagtacat ttttatctaa agcatccact tttttagctt caaaagcata
    18541 accttgctta gtagtctcta ctcccggagg acttgaacca ttaatctgag ccacattttg
    18601 tatagtctcc ccaactttta catttgtgaa gtctgcatca aatgtaaccc agctttgcac
    18661 aggttcccct tcttttatct gtttaaattc gtatttattt actaatctta ttgtattttt
    18721 tccatctcca gcttcttttt taagttcaag attatcagaa tattttatat tagatatttt
    18781 tagagatggg tttacttcat ccaaaagatt tacttgtcct gcatcataaa ccccataagt
    18841 tgacatattg attttgtatt taacaatctg gttatcacta ctatttaaaa cctttttatc
    18901 aacttctttt tttgcgctta ttaatccaga atttttctta aagtttatct catcattttt
    18961 atcaatttca ctattatttg catcaaggac agctctattt atataactat cttcaatact
    19021 aattaccttt aatgtataag ctataaaaaa ctttgattct acttcttctt tactgagatt
    19081 aattgtaaat ccagttataa ctttatctac ttgcccactt tcatttcttt tttcttctac
    19141 tttatatgaa atattattgg caattttttc tttactccaa ggagtccagc tcccattcat
    19201 tggaacttct acaactctaa aatcatgccc atcctctcct gaagtagtca atctcatacc
    19261 ttctggtata ttatctgtta taacaacatt acttattggt gatttatcat catttattga
    19321 aatctgatag tttattactt gaccaacttg agtaatattt gttgctcctg aatgtccttt
    19381 agtaagaaga taattatctc ctctatcaaa tatacttaca gtagcatcat cttcttgtat
    19441 cttcttacca tcagattcaa tcctagctac attcttatat ttattaccat gttttgcatt
    19501 tttgtcactg attctagcct tatacttaac agtatacgat ttatctatat ttccaaaatt
    19561 aactgaaata gaatttttac tctgttcaat attaaaatca ctaacttctt ttccatcact
    19621 tgttactaca cttacagaac catttatcaa tgtcaatcct tcaggaagct catcatacaa
    19681 aataatatct tttaactctt cctgcttttc atttacttgt atactgtaat ttatatcttt
    19741 atttttaact ggcataaata cagtagttga ttttcttcct tcaacaagct ttttaagtgt
    19801 tcctttagca tctggaacat ccgttttatc tccaggtttt atttctacat ctatatctcc
    19861 acttccactt tctatttttc cagtggtttc aatatgtatt tttgcattag tatcttcatc
    19921 aaccttttta acatatgctt ccaaacctat tttaccttgc attacacttt ggccattagg
    19981 taattctcta aatgtaagtg tatactctcc attactttct gttttatcaa agcattcact
    20041 tgtataatct aaattaactt tattgaatac atctggcacc ttaaaagtta ttgaatctcc
    20101 tgcttgtatt ccttttgatg ttggagtata agttaaatta aatgatattt ttttcattga
    20161 ttccgtttct attgtattgt tattaatttt tacaacaaat ccatagtctt cattaagttc
    20221 ttcttctaaa actttcaata aattttcatc ttctaataga ttatcttcct ctggagtttt
    20281 ttctgtattt ttattgtcta gtggtttttc atcttctaaa gcttgttctg actttttatt
    20341 atctgttgac ttatcttctt ctggtatttg ctctggcttt ttattatcta ttgacttttc
    20401 tccttctgga gtttgctctg gctttttatt atctattggc ttttctcctt ctggagtttg
    20461 ctctggcttt ttattatctg ttgacttatc ttcttctgaa gtctgttctg gttttttatt
    20521 atctgttgaa ttatcttcct ctggggtctg ttctggtttt ttattatctg ttgccttatc
    20581 tttctctgga gtctgttctg gttttttatt gtcgctttcc ttctcctctc cagttgatga
    20641 attagttgaa ccactttgaa tctgactatt ctctcctaat tctgaagcat aagatacagt
    20701 tggatatatt gtagacacca ccatacttaa aatcataatt aaactaatta ataatgcctt
    20761 tttatttcct ttcttcatat aaattttccc cctctaggtt atctatagtt tataatcttc
    20821 cattaatatc gtatataaat taatttttac taaaaaatta tataaaaaaa gctatgaaaa
    20881 taaataaatt tatattcata gccggttgca ccactgactc agtatatcca taaggtgccc
    20941 aataatagaa tatacttcaa catctctata atatttcata aaaacaatta aaattgcttt
    21001 atttatatta aaaatacaat tatatacttc tattatatta tgcctctata ctattgtcta
    21061 tcttttttac attttttacc ttttatgaga ttaattaata attaaataaa atccttatct
    21121 acaacaatta cacaattata ttcaggattt atctccttaa ctaattttgt tatatcttct
    21181 tttaagtcat cctctgacat gtctttggaa aattcggaag gattaactac tatatcaaat
    21241 attaaattct tcttgcttcc ttttccaact attctaaaat catgcataga ttttacaaga
    21301 ctatttttct taagtatttc ttcaagttct tttttggctg acataacttc tttatcttca
    21361 agacatattg ggtccatgtg aattactaga tatatatcta atttttcaga tatttctctc
    21421 tctgcagtat ctataatttc atgtatttcc attatatcta tgttggatgg aatttctgca
    21481 tgtatagatg caatacatct accaactcca tagttatgaa taattaaatc atgtgtacct
    21541 attatatatt tataagataa caatagctct ataatagaat ttaccatttc ttcatccggt
    21601 gcttctccta aaagaggatt tatagtatct tttacaagag agaaaccagc ataaagtatc
    21661 actaatgata ctacgatacc aacatatcca tctataggaa aattagtaaa tctagctaca
    21721 ataaatgata taactacaca acttgaagta aatacatctc ctaaagcatc aagtgaaact
    21781 gcttttaagg ctgaagaatc aattttattt cccacaaatt tattaaaacg actcaaccag
    21841 attttaatca ttatagatac aattaaaagt ataagtggta ttacttcaaa ttttacagga
    21901 attggattta ctatcctttc tatagatgac tttacaaatt gaagtccaac caacatcacc
    21961 ataaatgcta ctattaatgc tgataaatac tctattcttc catgaccaaa aggatgttct
    22021 ttgtcagctg gcttacttgc taatttaaaa cctatcatag ttattgctga agatgccata
    22081 tcagaaagat tattaaatgc atcagccatt atagctatac tagatgtgaa cattcctatg
    22141 aataccttta tcacaaataa aagtaaattg gacaatatac ctactacacc agctacataa
    22201 ccatacttat ttctaacatc tgtattttga acgttttcgc tatctctgat aaatgttttg
    22261 actaggattt tggaaaacat gaaacttacc tccctgccct ttattttatt aacaaatttt
    22321 ataatctata tctttattta tgataacata atttatatat aaaattctta aaaatcactc
    22381 tacttcagta aaatattatt ctatatatct atttagatac aaattttata tttcgtaaag
    22441 tttttatggc ttagtgtctg tttaatagat tctatataag tttttacaaa gattatttat
    22501 tatgataata tcatttttcc caagtattac ttagaatatg atttttttgt tttgtcttta
    22561 catattttaa atttatacta tatttatgtt tttataacct tatgatacac tataactata
    22621 agattttaaa cggaaaggaa tgaaataaat catgtttttt atcagtgata tttacacaaa
    22681 atcacctatt aaatttgata ctccattgca aaaagaggta tacaaaatat tacaaaagtt
    22741 agatattgac tttgaacgtg ttgacacaga tgaagcaatt acaatggaag attgtgttca
    22801 gattaataaa aaattaaata tgaaaatggt aatataaaac aacattaaac aaacaaaaac
    22861 cgcaaagtta caatatatag tactttgcgg tttcataaga attaattttt actattagag
    22921 ttcatacttc tactattttt cattgttcta agtattagct ttacaaattc atttgacaat
    22981 aatatagtgg atgcaaatag tattattttt atccacatat caaagtccaa agaaacagaa
    23041 ttaaagaaac tctggaacac ttgtgtaaat attatttgaa ttatccctgt aactactatt
    23101 atttgcaatg ccagtttatt tttaaagaaa tttggtattg tactatttaa accaaattct
    23161 ctacaattta atgcattaaa aagggcactg aacgcaaata aagaaaatat aacagtacct
    23221 tgttcttctg atgtagctcc caatatatta aaagctgatt gagtaaatac aattgtaatt
    23281 ataagaatag catttataat aatatttaca aacatagacc tagctattat tccagaatgt
    23341 ctatttattg gttttctttt caatacataa tctctaacag gttctaatcc taatgctagg
    23401 gctggaggac catccattat tatatttacc cataataatt gtattgtagt aaatggcata
    23461 tccttaccag taagttgaga tattatagca attataaatg ctactatatt tacagtaagc
    23521 tgaaactgta taaatctttg aaagttctca tatatacctc ttccccattt tattccctct
    23581 actatagtac taaagct
//
