LOCUS       NZ_CP115183            22365 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Clostridioides difficile R20291 chromosome, complete genome.
ACCESSION   NZ_CP115183
VERSION     NZ_CP115183.1
KEYWORDS    .
SOURCE      Clostridioides difficile R20291 (Clostridium difficile R20291)
  ORGANISM  Clostridioides difficile R20291
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP115183.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
            ##gutSMASH-Data-START##
            Version      :: 2.0.0-75c9ef8(changed)
            Run date     :: 2024-12-20 13:41:33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2660198
            Orig. end    :: 2682563
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22365
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2670198:2672563]"
                     /cutoff="10000"
                     /detection_rule="(cds(POR_N and TPP_enzyme_C and not
                     PFOR_II) and POR and not cds(POR_N and TPP_enzyme_C and
                     POR))"
                     /neighbourhood="10000"
                     /product="Phenylpyruvate_ferredoxin_oxidoreductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12365
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(cds(POR_N and TPP_enzyme_C and not
                     PFOR_II) and POR and not cds(POR_N and TPP_enzyme_C and
                     POR))"
                     /neighbourhood="10000"
                     /product="Phenylpyruvate_ferredoxin_oxidoreductase"
                     /protocluster_number="1"
     cand_cluster    1..22365
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(POR_N and TPP_enzyme_C and not
                     PFOR_II) and POR and not cds(POR_N and TPP_enzyme_C and
                     POR))"
                     /kind="single"
                     /product="Phenylpyruvate_ferredoxin_oxidoreductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22365
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Phenylpyruvate_ferredoxin_oxidoreductase"
                     /region_number="14"
                     /rules="(cds(POR_N and TPP_enzyme_C and not PFOR_II) and
                     POR and not cds(POR_N and TPP_enzyme_C and POR))"
                     /tool="gutsmash"
     gene            complement(111..947)
                     /gene="nadC"
                     /locus_tag="O9S30_RS12460"
                     /old_locus_tag="O9S30_12460"
     CDS             complement(111..947)
                     /EC_number="2.4.2.19"
                     /GO_function="GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA]"
                     /GO_process="GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nadC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QRPTase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QRPTase_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /locus_tag="O9S30_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12460"
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="WP_004454666.1"
                     /sec_met_domain="QRPTase_C (E-value: 8.9e-61, bitscore:
                     202.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="QRPTase_N (E-value: 1.2e-28, bitscore:
                     96.8, seeds: 125, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQDG
                     IIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYLQR
                     MSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGILLK
                     DNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSLEMAK
                     QAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLRNI"
     gene            complement(928..2229)
                     /locus_tag="O9S30_RS12465"
                     /old_locus_tag="O9S30_12465"
     CDS             complement(928..2229)
                     /EC_number="1.4.3.16"
                     /GO_function="GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 273.6; E-value:
                     1e-83)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /locus_tag="O9S30_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12465"
                     /product="L-aspartate oxidase"
                     /protein_id="WP_003430790.1"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.3e-82, bitscore:
                     273.6, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYLA
                     QGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKENG
                     EIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGNKCI
                     GARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIENLEYI
                     QIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFEQMEKD
                     KLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGIHVDLDS
                     KTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKVKFIDVPD
                     MDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(2242..3156)
                     /gene="nadA"
                     /locus_tag="O9S30_RS12470"
                     /old_locus_tag="O9S30_12470"
     CDS             complement(2242..3156)
                     /EC_number="2.5.1.72"
                     /GO_function="GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NadA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /locus_tag="O9S30_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12470"
                     /product="quinolinate synthase NadA"
                     /protein_id="WP_009890564.1"
                     /sec_met_domain="NadA (E-value: 2.8e-117, bitscore: 388.9,
                     seeds: 602, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLSE
                     IARDCKEEVVVFCGVRFMGESAKLLSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQYP
                     NALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFPDKN
                     FIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGIIKYAT
                     NSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKNMENEV
                     IVEDEIMEKALNSLLNMHKLAEG"
     misc_feature    3187..3202
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.97"
                     /tool="gutsmash"
     misc_feature    complement(3335..3348)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.26"
                     /tool="gutsmash"
     gene            3574..5031
                     /locus_tag="O9S30_RS12475"
                     /old_locus_tag="O9S30_12475"
     CDS             3574..5031
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /locus_tag="O9S30_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12475"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_009890565.1"
                     /transl_table=11
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDYV
                     PMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMISIR
                     EKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTINNP
                     VVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLANLSL
                     ANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNMMILEG
                     LIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLPITSGDT
                     ALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILWRYFSWSN
                     QTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNINISYVLAA
                     IFTVLYAILTVRSGRKLKSKADTKLAD"
     misc_feature    complement(5060..5073)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.47"
                     /tool="gutsmash"
     misc_feature    5073..5089
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 23.68"
                     /tool="gutsmash"
     misc_feature    complement(5105..5121)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.69"
                     /tool="gutsmash"
     gene            5254..5682
                     /locus_tag="O9S30_RS12480"
                     /old_locus_tag="O9S30_12480"
     CDS             5254..5682
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /locus_tag="O9S30_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12480"
                     /product="hypothetical protein"
                     /protein_id="WP_003430796.1"
                     /transl_table=11
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTKP
                     DFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLENNF
                     KCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            5742..6050
                     /locus_tag="O9S30_RS12485"
                     /old_locus_tag="O9S30_12485"
     CDS             5742..6050
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /locus_tag="O9S30_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12485"
                     /product="DUF1540 domain-containing protein"
                     /protein_id="WP_003430798.1"
                     /transl_table=11
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASFE
                     DKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK"
     gene            complement(6197..7219)
                     /locus_tag="O9S30_RS12490"
                     /old_locus_tag="O9S30_12490"
     CDS             complement(6197..7219)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /locus_tag="O9S30_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12490"
                     /product="AI-2E family transporter"
                     /protein_id="WP_003430799.1"
                     /transl_table=11
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTFI
                     FYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSRVF
                     SDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLLSLL
                     LLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVVSMIF
                     LGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMICIVHA
                     VETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILGVKFTSR
                     "
     misc_feature    complement(7279..7288)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="gutsmash"
     gene            complement(7394..7900)
                     /locus_tag="O9S30_RS12495"
                     /old_locus_tag="O9S30_12495"
     CDS             complement(7394..7900)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /locus_tag="O9S30_RS12495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12495"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_009890566.1"
                     /transl_table=11
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQIL
                     IQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIHED
                     TLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEMYELLYEIDN
                     NKLNI"
     gene            complement(7959..8660)
                     /locus_tag="O9S30_RS12500"
                     /old_locus_tag="O9S30_12500"
     CDS             complement(7959..8660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /locus_tag="O9S30_RS12500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12500"
                     /product="membrane protein"
                     /protein_id="WP_009893594.1"
                     /transl_table=11
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLSI
                     KLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASNTY
                     IGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILALVV
                     GWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKRSNEHKC
                     KSSIVIKNEQN"
     gene            complement(8878..9948)
                     /gene="buk"
                     /locus_tag="O9S30_RS12505"
                     /old_locus_tag="O9S30_12505"
     CDS             complement(8878..9948)
                     /EC_number="2.7.2.7"
                     /GO_function="GO:0047761 - butyrate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /gene="buk"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /locus_tag="O9S30_RS12505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12505"
                     /product="butyrate kinase"
                     /protein_id="WP_004454677.1"
                     /sec_met_domain="Butyrate_kinase (E-value: 5.3e-126,
                     bitscore: 417.8, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTIQ
                     DQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPVLE
                     HASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTRAMA
                     LKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVPATKL
                     VAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAMAYQLA
                     KGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELESLAFGT
                     LRVLNGEEEARIYSEN"
     gene            complement(10001..10576)
                     /locus_tag="O9S30_RS12510"
                     /old_locus_tag="O9S30_12510"
     CDS             complement(10001..10576)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Phenylpyruvate_ferredoxin_oxidoreductase: POR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /locus_tag="O9S30_RS12510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12510"
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="WP_003430806.1"
                     /sec_met_domain="POR (E-value: 3.4e-38, bitscore: 129.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQRG
                     GSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSMTV
                     LIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESIDWE
                     KIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(10578..12365)
                     /gene="iorA"
                     /locus_tag="O9S30_RS12515"
                     /old_locus_tag="O9S30_12515"
     CDS             complement(10578..12365)
                     /EC_number="1.2.7.8"
                     /GO_function="GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="iorA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Phenylpyruvate_ferredoxin_oxidoreductase: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Phenylpyruvate_ferredoxin_oxidoreductase: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /locus_tag="O9S30_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12515"
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="WP_009890567.1"
                     /sec_met_domain="POR_N (E-value: 1.3e-17, bitscore: 62.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.5e-28, bitscore:
                     95.5, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_9 (E-value: 2e-07, bitscore: 28.9,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.12, bitscore: 10.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDAI
                     VAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLITAD
                     EPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVTTRL
                     CHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNETDLNY
                     YEMNDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKIYVIEE
                     NDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVTPRPPSF
                     CAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTAHGAQKVL
                     NMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTGHQENPGSG
                     YTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEPSVIITRWPC
                     VLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENKLSNIDRNQCV
                     GCGVCAQVCPKQAIVKEEK"
     gene            complement(12426..13685)
                     /locus_tag="O9S30_RS12520"
                     /old_locus_tag="O9S30_12520"
     CDS             complement(12426..13685)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /locus_tag="O9S30_RS12520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12520"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_009890569.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-34, bitscore:
                     118.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIGA
                     LMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIRVL
                     ASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRFNFE
                     SFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKIIFFV
                     DSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICISSSEDV
                     AEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTRRADVFV
                     EEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVCAVSEDKC
                     KKAPSIIKEALESLEVKINN"
     misc_feature    complement(13730..13743)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="gutsmash"
     gene            complement(13947..15947)
                     /locus_tag="O9S30_RS12525"
                     /old_locus_tag="O9S30_12525"
     CDS             complement(13947..15947)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /locus_tag="O9S30_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12525"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_012816275.1"
                     /transl_table=11
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLME
                     NQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVVLI
                     LGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACSFAR
                     QYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAIDSNGS
                     IILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINNLIVNT
                     RTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKDKLTREF
                     IEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAENLLESEL
                     FGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEERQIMRIGSD
                     YIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRREDIIPLFNNFV
                     NEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYVVTGKIKLRQD
                     RDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKEVNKYVEEKIIS
                     MLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(15955..17784)
                     /locus_tag="O9S30_RS12530"
                     /old_locus_tag="O9S30_12530"
     CDS             complement(15955..17784)
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454680.1"
                     /locus_tag="O9S30_RS12530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12530"
                     /product="diguanylate cyclase"
                     /protein_id="WP_306316136.1"
                     /transl_table=11
                     /translation="MLTKFYLNLTDLNYILDYHKDLLNTKLEDNSRVYTLYLISLINYI
                     KKDREASYNYLIESLKYIKKLSLKEDSDIISKIYIYLTLSAISIRKYDKANNFYFSAKK
                     VIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVEEVSFFKTLKNKALVSRANYIFG
                     RVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFCKCIISLCYLESGNNVEAIKYINN
                     VLDVAHSKNSISVTERVSIKIDLIWAYLKEDMNKEAEVILLKTIKLMKVVEGVYKDYLY
                     SFIFLYSAEIELRKDNCSFEKVNTYLILSKNIYKSFGDVFIYNSKLDYIYKLYGDLYIK
                     FGNIDEGISCYIKGLNLVKKSSLNLRKISIFYGLIANGYELKKDFKLAIEYYKSMDWYS
                     DRWEKNNSYKTSQAIHKQYELRQKQESLRLLVDDNKKLENDILKDGLTKLYNRRYLEQQ
                     LDLFNGTRDKNMVAILVDIDCFKSYNDNYGHLAGDKVIVKVTDIIRSVFIDITEHIIRY
                     GGEEILILVDSIESIGVEEIDNIELYIKRVFKLLEFEGIEHIYSKIKNYITISAGVSIK
                     RCRSRKDVEILIEDADKNLYKSKKAGRNQYIII"
     gene            complement(17868..19709)
                     /locus_tag="O9S30_RS12535"
                     /old_locus_tag="O9S30_12535"
     CDS             complement(17868..19709)
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /locus_tag="O9S30_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12535"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_009893596.1"
                     /transl_table=11
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFVENKIGVVKNLIDCYKTE
                     QNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAILS
                     LKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIETLYI
                     KIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLCNIKI
                     GECECSFENYECSIEYLNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVAINNLA
                     KSEVYLEKIKNQSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILNMIKNIE
                     EYTIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKNIYLCFEK
                     IQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIETEINNMRKVKLDLDKKKY
                     VDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDIALKNITIII
                     KKYLKKDMFMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNLTVSIGIDTCK
                     NSSIDIREIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(19840..20259)
                     /locus_tag="O9S30_RS12540"
                     /old_locus_tag="O9S30_12540"
     CDS             complement(19840..20259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /locus_tag="O9S30_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12540"
                     /product="DUF3785 domain-containing protein"
                     /protein_id="WP_004454682.1"
                     /transl_table=11
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILNE
                     AEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGLSF
                     NKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            20572..20754
                     /locus_tag="O9S30_RS12545"
                     /old_locus_tag="O9S30_12545"
     CDS             20572..20754
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O9S30_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O9S30_12545"
                     /product="hypothetical protein"
                     /protein_id="WP_003430814.1"
                     /transl_table=11
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMVKYGENIVDS
                     NLHSIMMLLCKWGLS"
     misc_feature    complement(20773..20791)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.64"
                     /tool="gutsmash"
     gene            21085..22107
                     /locus_tag="O9S30_RS12550"
                     /old_locus_tag="O9S30_12550"
     CDS             21085..22107
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glu_synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /locus_tag="O9S30_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12550"
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="WP_009890571.1"
                     /sec_met_domain="Glu_synthase (E-value: 4.7e-06, bitscore:
                     23.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSF
                     IENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEKEY
                     IEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNSGNGIVFIKPWNNSKIIEKIRLS
                     EEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTKLPFIIKGIMTVDDALM
                     AVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLG
                     LGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGRVIWNLL
                     "
     gene            complement(22192..22365)
                     /locus_tag="O9S30_RS12555"
                     /old_locus_tag="O9S30_12555"
     CDS             complement(22192..22365)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890572.1"
                     /locus_tag="O9S30_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O9S30_12555"
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="WP_009890572.1"
                     /transl_table=11
                     /translation="MHLVQLLCQQINGSDIDPDSKFGPATYNQVKILQGRLGVTKDGVV
                     GKATWQAVGERY"
ORIGIN
        1 attgattttt ttatattttt attaatttta atgaataaaa aatagactcc ttaaatttat
       61 aaaacaaatt taaggagtct attttaatta agtttatttc aatataaaac ttatatattt
      121 ctcaaattct tcatacttat atcgagagct ttaacagaat gtgtaagcgc tcctacagaa
      181 acaacatcca caccaatttt tcctatatct tctatagtat ctaaatttac atttccggaa
      241 aattctacaa tggctcttcc atttataata tctactgctt gttttgccat ttccaaactc
      301 atattatcca acattattat atctgcatta gcttctattg cttcttttac catgtctaaa
      361 gtttccactt ccacttctat ctttctaaca aaagaagtat tttttctagc taattcaact
      421 gccttcttaa cactaccagc agccccaata tggttgtctt taagcaatat tccatcagat
      481 aaattaaatc tatgattgca tcctccacct actttaacag aatacttatc taatattcta
      541 agattaggta tcgtttttct actatctaat aattttgtat ttgtaccttc aagcttttca
      601 acatacctac ttgtaatagt agctatacca ctcattctct gtaaataatt caatgctaca
      661 cgctctccta caagtaagtt tctagtacta cctgttaata cagctatctt ttcacgattc
      721 tttactctat caccatcatt tttatataat tttacatcta catcaccaag tatctcaaaa
      781 actctcttaa atacacctaa gccagctatt ataccatctt gtttgcaaat taaatctaca
      841 gtagatttag aattttcatc cacaatagaa ttagttgtta tatcttcact tggaacatct
      901 tctatcaaag catcctgtat cattctatca ataatcaaat aattcatcgc caaaatcctc
      961 acttgttctt tcaatttctt ttatgactaa tattttattt tcttttttta cctgttctat
     1021 atctatatcc atatctggta catctataaa cttaactttt acattatcta taactgagtt
     1081 tatattttta gctgctcttt ttgaaaatac aagcccttca agtaatgaat tacttgccaa
     1141 tctattggct ccatgaacac ctgtacaact aatttcacca actgcatata aattttccat
     1201 agatgttttt gaatccaaat ctacatgtat cccgcccata aaataatgtt gtgcaggaga
     1261 tacctttata cattctttcg ttatatctgt tcctctagct aaacattcat tataaataaa
     1321 agaaaatcta ttaattaaat attcactatc taaatgtgtt gcatctaaat acacataagg
     1381 taatttatct ttttccattt gctcaaaaat agcttttgaa actacatctc taggaagaag
     1441 ttcatccaca aatctttctt tatttttatt taaaagttta gctccctctc ctcttaatga
     1501 ttcagatata agcattctcc taccttcatt attttcttca taaaaggctg taggatgtat
     1561 ttgaatatat tctaaatttt ctatttttat attatttctt aaagctattg caattccatc
     1621 acctgtaaga tgtctttgat tagtagaatt tttaaaaagc ccaccaattc cacctgtagc
     1681 taaaactact atttttgaaa aaacatgaat ctctttttta gatttaaaaa ttctagctcc
     1741 tatacattta ttgccatctt ttaatatatc taaaagatat gcatcttcta taagagttat
     1801 attttctcta gttttagctt cttttaataa agttttaaaa acaacttctc cagtattatc
     1861 cttactatga actattcgat ttacactatg tgctccttct cttgtgtaat ctatctctcc
     1921 attttctttg tctaaaggca taccatattc tactatctgc cctacatttt ctatagattc
     1981 atctgcaagt acttgaactg cttcaactct atttttatac tgcccagcct tcattgtatc
     2041 ttctacaaag gattctatat catcaatatt tctagcagtt gaaattccac cttgtgcaag
     2101 atatgtattg ttgttttcaa ttgttgattt cgatactact agcacattta aacttttatc
     2161 taaatttaat gcacagtata atcctgaaac tccacttcca actattaaaa catcttgttc
     2221 taaattcata agtctatccc tctatccttc tgctaatttg tgcatgttaa gcagtgaatt
     2281 taaagccttt tccatgattt catcttctac aataacttca ttttccatat ttttaagtgt
     2341 actatataaa ttttctaatg ttgtcttttt catatctgta catagtattt ttccaccagg
     2401 aatataaaag tttttattag gattattttt ctttaattca tgtaatatac cttcttcagt
     2461 tgctattata aagtctttgt ttttactatt agtagcatat tttattattc cggatgtact
     2521 acctacataa tctcctaaat ctcttatttc ttttttacat tctggatgta ctaatacttc
     2581 tgcattttta tacttatctt ttaattcaat tatttcttca gctcttatat tgttatggta
     2641 tttacaatat ccgtcccaaa atataaagtt tttatctgga aattgttctg caatatatcc
     2701 tcctaaattt ttatctggaa ggaatataat ttctttatta tctatgtttt ctagtatttt
     2761 aattgcacta gaagatgtaa cagaaacatc acaatgtgcc ttaactttag ctgtagagtt
     2821 tatataacat acaaccaaag catttggata ctgttgtttt aattttatca cgccttcttc
     2881 atctaccata tctgccatag cacacccagc gttacttact ggcatcaata cagttttttc
     2941 aggtgataat agcttagcac tttctcccat aaaccttact ccacaaaata caaccacttc
     3001 ttctttacaa tctctagcaa tctcacttaa ataatatgag tcaccaactg catctgctaa
     3061 ttcttgtatt tctggtggtt gataaaaatg ggcaagtatt attgcatttt tttctttctt
     3121 tagctctttg atttgatatg ttaaatcttt atccataatt gcaccgcttt ctatatgtac
     3181 tagtgtatat acacctgtaa acccattata tcacttgact attctttctt caagaatttt
     3241 aaacctctta atattgttaa gatatagaca tttatattct caattgattt tccttttttc
     3301 tccatctatt taaactaatt tttatatttt ttaatttttt tgtaaaatat tatcagaatt
     3361 ttgtttatat tctttattgc tataacattg aaaatattac caaatacctg tatactaagt
     3421 acatggttat gtatatgtat ttatttctga aattatatta gttgtaatac tttatagaat
     3481 ttgtaggttg tccagaatta aattcaatat aaatctacac atttagataa tatgtataca
     3541 aagaccaaaa aattttataa atggggtgat attatgacaa cattcttaat cggcttggct
     3601 atattactaa taggaggtgc tttatacggt gcttattgtg aaaaagtatt tggcccagat
     3661 gacagaaaaa cacctgcact tgctcaaagt gatggagtag actatgtccc aatgaaaaaa
     3721 tggaaaaata gtctaattga gttgcttaat atagctggta caggaccaat tctaggacct
     3781 atccaaggta tattgtttgg tccaatagca ttcatactaa tacctattgg ctgtgtattt
     3841 ggaggagctt tgcatgacta tatgagtgga atgattagta taagagaaaa aggagcacaa
     3901 atgccttctc ttatcagtag atttttaggt aataaagtat ttcaagtcta taatatattc
     3961 ctttgtcttt taatgctttt agttggtgca gtttttattt atacacctgg ggatttagtt
     4021 gttactcaaa ttttaaatat gaaatcgact ataaataatc cagttgtctg gatagtttat
     4081 ggacttatct ttctatatta cttgtgtgca acactctttc caattgataa aatcatagga
     4141 aaggtatatc caatatttgg agctattcta cttttatctg ctgctggtgt tggaattgga
     4201 atctttacac aaggttatga tttagctaat ttaagtcttg caaattggaa aggtattcat
     4261 cctgatggta ttcctcttat tcctacattc tttgttacag ttgcttgtgg tatcgtttct
     4321 ggattccact caactcaagc tactcttata gcaagatcag tttcaaatga aaaagaagga
     4381 aaaactactt tttataatat gatgatttta gaaggtttaa ttgcaatgat ttgggctgca
     4441 gctgctatgg gtatttacaa taaaggaata cctaaggaat tagtaggttc tcctgatgta
     4501 ataggtttgg ttgcaagaga tttacttggt tctattggtg gtatcatagc tataataggt
     4561 gtaattgttt taccaataac ttctggagat acagctttaa gatctttaag attaatgctt
     4621 gcagattact ttcattatga ccaaaaggaa aagaaacatc gtgttatatt gtcaatctgt
     4681 atatttattc ctgtcatagc cattcttata tttgcaaagc ttagtgcttc tggatttaat
     4741 atattgtgga gatacttctc ttggagtaat caaactattg ccatatttgc atttgcaatg
     4801 attacagttt accttataat aaaagaaaag aattatatta taagcttaat tcctggtatg
     4861 ttttattctt ttgttatatt cagttatata tttaatgctc aaattggatt taacttaaac
     4921 ataaatatat catatgtttt agctgccata tttactgtat tatatgctat tttaactgta
     4981 cgctctggta gaaagttaaa aagcaaagcg gatactaaat tggctgacta aatctaaata
     5041 aaataatact tagaataaat tttattaaaa aatgataaaa aagtaggcaa tctcaagtta
     5101 gatttgcctc ttttttattt aatacagtaa taaatactta agtatttact ccttattgga
     5161 atatttatcc taaatctcta atataaataa ataaaagttt taaaataatc tattcattta
     5221 tatacttaaa ataaattttt tggaggaata cttatgaata ataaattaca tgaacttgaa
     5281 aaaaatctac cagaaacatc ttgttctttt tgcacacatc tttcatttaa ggggcctagc
     5341 ctagactata gatatgatat tagatgtgtt atttcagata caaagcctga ttttagagga
     5401 tgttgtgaat attttgaacc agaatataca gaattaaata caggagattt agacaatcta
     5461 tacataaact ttcttgagac atgcctcaag gtaaattata atgattacat caattctatg
     5521 tattggaagt tatttaaaga aagaacccta ctagaaaaca attttaaatg ttctatatgt
     5581 ggatcaactg aaaatgttga tgtgtatcat gttaataaaa atttaggaag ggaaacttcc
     5641 aaagatgtag ttgttaaatg tgataaatgt aattgtaaat aagtgtataa aatttagata
     5701 acttcacata ataagtttaa ataaaactta ggaggttatt tatgaaaaat aataatttaa
     5761 attgtgctgc tactaattgt gcttataata ctagtggata ttgttatgct ggtagtataa
     5821 aagtagatgg aatgcaagca actactacag aaaatactta ttgtgcttct tttgaagaca
     5881 aatatacatc tggtataact agtcgttcta atgaaactaa ccaagttgat acagataaca
     5941 ttcattgtga agctgtaaaa tgtaaataca ataaaaatga actttgcaaa gctgaaaaag
     6001 ttcatataaa tgaaagaaat gcaagttgtg aaacttttga aatgaaataa atttcttttt
     6061 atttaattct atagtattta tacaaagcaa aattgaacct atcaaataga tgtctttatt
     6121 aatgatgtct atttataggt tcttttttaa aacaattcat aatttatata taaaaataaa
     6181 ttattatttt aatatattac ctagaagtaa atttaacacc cagaatatcc ataaggaaca
     6241 taaatattgg aactccaatt agtaatcccc atacacctaa ataatgttct cctacaagta
     6301 aaataataaa aacaaaacaa actggaagtt tagttctatt cgacatcaac ttagggttta
     6361 atatgtatgt ttctactgca tgcactatac aaatcataag taaaactcca aaaacctttg
     6421 ttattcctcc tgtattaaat gctattacag ttaatggaat caaagacact ataactcctg
     6481 ctactggaat aagacccaac acaaaaatca taaatcctaa agcccatatt tgagggaatc
     6541 ccatgaaacc taagaaaatc atagaaacaa cagaatttat aaaggcaatc ataacttgta
     6601 ctttcattac ttcaccaaaa tttttaacaa agctctttcc aaaaaataca agcgaattat
     6661 aaataaaaga aatcttacta tcagaaagtt tatctccaaa atttttaatt tcattttttt
     6721 caagtaaaag gagtaaactc agtaaaaatg ccaataatat atttactcca aaacttccaa
     6781 cttttgttgc tgttgatgct ataagtagcc ctgcttgtga aatatattta ttaaaatcca
     6841 gctttgagac aataggatac aattttggtc ctaaagattg agcaaattga tttacatcaa
     6901 aatcactaaa aaccctactc agctctgtaa gttgaactat aattattggt acaactgcat
     6961 agctaatcaa tactaacaat atagcaaata gtgcatataa cactataatt atcaatgaat
     7021 ctggaatatt taaagaagaa aacttcttaa ttcgttttct tgtggctaca agcaagttat
     7081 agaaaataaa agtcataata aatgttaaaa gcaccatatt taacatatac caaaatgtaa
     7141 ttagaataat tactacgaca gatatagaaa caattttata ttttgaacta tcacgtgcca
     7201 atcctttgtt atcttccata gtttaaatcc tccccaaatt tttatgactt tataatgact
     7261 gcccttttta ttttaatctc aaaaaacaag tagaaaaata ctaaaaataa cttattaatt
     7321 ttcataaaac aatattaaaa tttagagaag atacatttta aataatctta cttatactga
     7381 aatctgctct acatcatata tttaatttat tattatctat ctcatatagc aattcgtaca
     7441 tctctggata ttcaaaaaac aaaccctctt ttagtaattg tcttatttca tctgtgctta
     7501 cccactttat atcacttact tcttcctcct gtaaaatagc tttggatata tcatattctt
     7561 ttttaactaa gtatacatcc caaagagtat cttcatgaat catacttcta aaaactttca
     7621 tctcatcttt agttatatct atccctattt cttcctttgc ttcgcgaatt gctccttcta
     7681 aactatcttc cccagaaaca atacatccag ttgtcattcc ccacatattt ggcaatgtct
     7741 ttttactttt agaccttttc tgaattaaaa tttgagagtt actatttaaa atccacactt
     7801 caactgccaa atggtaataa ccttcttcaa tagaattacc tctttttata acatttcctg
     7861 ttttaattcc atcagcatta tataaatccc ataattccat ttcaaaatct cctgacttta
     7921 ctataaatta gataaactac aaatatattt tagcataatt aattctgctc attttttatt
     7981 acaatacttg atttacattt atgttcattg cttctctttt ccttccattc tcttatatca
     8041 tctataataa atctatgttt cagcaacttt gtgtcaaatt taaatattct aaacactatt
     8101 tgtaatacat atcctaaacc taaagcactt acaagcgtac caatacctac agaacctcct
     8161 aataaccacc caacaactaa tgctagtatt tcaagaattg ttctaacaag acgtacagat
     8221 ttattagttt ttttctgaag agcaatcata agcccatctc tcggtccact tcctaaacaa
     8281 acacctaagt atagaaaact tgctatagct gccaaaataa ttcctataac aaccataaac
     8341 acacctatat aagtgttgct tgcatgaggt atcactccag aaaatattac taaatcaata
     8401 aaaattccta taaatgtcat gttgagtaaa gtaccccatc ctatattttc accaaaaact
     8461 gcatccaata taacaattac aactcctacc attatagaag cctgacctat agttatgcct
     8521 agctttatag ataaaccttg gtgaagtaca tcccaaggca taagacctac atgtgcatta
     8581 atcataagca cagaagaaat tgcaaatata aaaaaacctg aaaataatct tatcatactt
     8641 tttaaactta tttttcccat caaaaatcac tcctcataat aataataaca ataaatacca
     8701 ataaaatata tatataaata cgaaatttta cagaattatt tattagatta agataaaatt
     8761 ttaattataa aaagtggcaa tccaaatttt atacattttc acctatactc taagctttcg
     8821 tgtataaaaa acggatatac cactttttta gtatataaac atttttaatt tttcttatta
     8881 attttcacta taaattctag cttcttcttc tccatttagt actcttaaag ttccaaaagc
     8941 aagtgattcc aactcatttt ctcctgccat aatttctact ggtgctataa actcaacttt
     9001 ctttttaacc attgaagtaa acatttcaga atatgcaatt ccacctgtta taattatagc
     9061 atctaccttt ccatctacta cagttgctaa ctctccaata ccttttgcta actgataagc
     9121 cattgcttca taaataattt ttgcttcttc atttccttct gctatcattt tttcaacttc
     9181 tctagcatct acagtattta ggtatgaaac tataccacct ttacctctta tctttttagt
     9241 catttctctt tctgaatatt gacctgaata acaggcagcc actaattttg tagcaggtac
     9301 tcttcctgac ctttctggag aaaatggtcc ttcatcatca gatagcatat caaccattct
     9361 tcctttttca tgaagataaa tacttactcc tccaccaatg tgagctacta ttaagtttaa
     9421 gctcttataa tcttttcctt tatccttagc atattttaaa gccattgctc tagtatttaa
     9481 tgcatgccct gcacttgatc tatccattcc acaaagtcca gatattctcg ctacatctat
     9541 aagctcatct actgcaacag aatcataaat atatgagttg attccaagag gttctgatat
     9601 tgcatgtgcc acaacagcac ctaaattgga agcgtgttca agtactggtc tatgtcttag
     9661 tacatcaatc atttcttcat ttactagata tgctcctgat tttactggtg gtaaaactcc
     9721 acctcttcct actattgcac taagagattt taagtctata ctattttctt taagaatatt
     9781 caaaactgct tccttacgca tttcaaactg gtcttgtata gtattatatt ttgcaatctc
     9841 ttcagctgga tggtctatcg tcttcacaag aatttgttct tctccatcat atactgctat
     9901 ttttgtagaa gtagaacctg gatttatggc taatattctg taagtcataa ttttcttcct
     9961 ttcaccttaa tttctatagt ctatttatat ctattataaa ctatttgcta accatttcca
    10021 taccttcatg gaaagctttt atgtttaatt caacaaattt tggtttaaca ttttcactta
    10081 taattttttc ccaatcaata gactctaatt gcatagattt aactagacat cctaataaaa
    10141 taacattcat tatttttgaa tttcctagtt cttcagcttt atcagctgca tttataactt
    10201 ttgcatttaa tctacttaac tctgcatcta tatcactttc ttgatattca gctcctccga
    10261 ttaaaacagt catagaatct atcctatgat tatttactaa agcttttcct tctggtttta
    10321 aataattgaa ccatcttaaa gcttccattt tttcaaaaga tactaatata tctgctccac
    10381 caatttctat aactggagaa tgaacacaat ctccatatct aacttgtgag gaaactgaac
    10441 ctcctctttg actcattcca tgtatttcac tcatctttac atcatatcca gcttccatca
    10501 atcccatagt taataattta ctagcaagta tagttccttg acctcctaca cctaccaaaa
    10561 gtatactctt agtcatatta tttttcctcc ttaactattg cttgttttgg acaaacttgt
    10621 gcacatactc cacatcctac acactgattt ctatctatat ttgataactt attctcttta
    10681 tcaaatgata gagctggaca tccagttttc aaacataatt tacatcctat acatttatca
    10741 tggtcaactt tacacttagt cttaaatgga ttattaaatt cttctatatc ttctttagag
    10801 aattttttaa gtacacatgg ccatcttgtt attattactg atggttcatc ttctatagct
    10861 aaagcccaat ctagtgcttc atttacttct tttaaattgt tagggtttat aactcttaca
    10921 tgttctattc cacaagcttt aactaatcct tctatatcaa cttctttagt tttagcacct
    10981 tgtaaagtat accctgaacc tgggttttct tggtgacctg tcattccagt tattctatta
    11041 tctaatataa ccgaaataga attacctcta ttgtaaacaa catctaaaag tccatttatt
    11101 cctgtatgga agaatgttga gtctccaagt acacctacca atcttttttc attatcatcc
    11161 ttcatattaa gaactttttg agctccatgt gcagttccaa aagcagaacc catacaaaca
    11221 acataatcta ttccattata tggaggagca aatccaagag tataacaacc tatatctcca
    11281 ccaactatta aattttttct ctttccaagt tcatagaaga atcctctatg tggacatcct
    11341 gcacagaaac ttggtggtct tggtgttact aattcagatt tgtattctat agtatcattt
    11401 gtttttccaa atatagcttt tcttaaaaca tctggtgtca tttctccata tggtggtatt
    11461 acatcttttc caatacaatc tattccatat gcttttattt gttcttctat aaatgggtca
    11521 ttttcttcta taacatatat tttatcaact ttttctgcaa attcttttat tttttcataa
    11581 ggtaatggat ttgtaaatcc tagtttcata tatgatgcat tttttccaaa aacttctttg
    11641 gcaaaattac aacacatacc agaagctata acacctattt ttgtatcatt catttcatag
    11701 tagtttaaat cagtttcatt tgagaatttt ttaaggattt ccattctttc ttcaacaacg
    11761 ccccttctta tttgagcatt tgctggaaca gttaccattt tcttagcatt tttaacatac
    11821 tctttaattt caacttcttc tctatcatag cactccacta atccttttga atgacaaagt
    11881 cttgttgtaa ctctatataa aactggtgta tcgtattttt cactaacttc aaaagcttct
    11941 tttatcatat ctttagcttc ttgactagtt gatggttcaa ataaaggtat ctttgcaaat
    12001 tttgcataca tcctattatc ttgctcattt tgagatgaat gcattcccgg ctcatctgct
    12061 gtaataagta ccataccacc atttacccct gtatatgcat aagtaaatat tggatcagct
    12121 gcaacattca aaccaacatg tttcatagaa gccattgttc ttgctcctgc aattgaaccc
    12181 cctatagcag cctcaagtgc taccttttcg tttggagccc actctgcaac tattgcatct
    12241 ttatatgttg ctatattttc taatatttct gtacttggag tccctggata tgcagatgca
    12301 tatttaacac cagcctcata ggctccacgt gcaattgctt cattacctgt catcaattgt
    12361 ttcatataaa attccctcca tctacaatta ttaaattcat agtccaccca atttgttcaa
    12421 tgaaattaat tatttatttt tacttctaaa ctttcaagtg cttcttttat aatacttggt
    12481 gctttcttac atttatcttc agaaactgca caaactgcaa atcttaagcc catttttaat
    12541 ggaactgcaa ataaattatg tttagtcaat tcttcacata cttcttttgg attatcacat
    12601 ggtatactta caaagaaacc tgctatatat ggaagaattt ctaatcctac tctttcagct
    12661 tcttctacaa atacatctgc tcttctagta agcatgtttt tgtatatttc tttttcatcc
    12721 tcatattctt tgaatttttt agggtcattt acaatgttag ataatactgc catggcactt
    12781 ctattacaat ttgaccaatt tgctctacat gaatgaacac atgagtaatg gaactcttca
    12841 gctacatctt cacttgaaga tatacaaatt atagccccca ttctcatacc ataagctgta
    12901 aatccttttg acatactgaa tccaaccaat acgagaacgt tttcaggcaa attagaaaat
    12961 ttcttaaaaa actttctaca tacatcatca tcacctgcaa agtcaatata tgctgaatct
    13021 acgaaaaata ttatcttttt gtctttatct tttgcgactt cttttgataa gtctaatatt
    13081 ttatcccact catcatctgc aacactatat ccagttggat tatgcgctgg tgtgtttata
    13141 attgtaaaga ctctaccttg tttttctgct atatttacaa atttttcttt gaacgactca
    13201 aaattaaacc ttctattttc atcaaaaagt tggtaattaa ctacttttct attagcctct
    13261 tcagctatac ttacatatgg actccaaaac caatcagatg ttaatacctc atctccttca
    13321 ttagtatagt tccatacagc taattttatt gcaccacttc ctcctggtga agctaatact
    13381 cttatatgtc cttctggtaa gtaatctctg aaaaatactt ttttaactgc ttctaagtag
    13441 tctggttgac cttcaagagc tgcatatgca cctatctcac agttatctaa tgctttatat
    13501 tcttcatata cagttttcat tgttattaat tttcctgaat catccattag agcgcctatt
    13561 gttgcattta ttacattatc cataccaaaa gccttctctg ctgcttgagc tctaccagat
    13621 atgctaaata taacatcatt ttcttttggc cacattgcat gcttaccaac catactttga
    13681 ctcataccat cacccctaaa attgtattta ctcttacatt atatattaag caattactat
    13741 gccaataaat cccactttat gtaaaattga ttttgtttag aattattatt tttttcatta
    13801 ttaaattaag tgttttaact atttttctta taaatatata tgcctgtcta aaaaaataaa
    13861 aatttacaaa aaagtaatgt taatttttct taacacttgt tttaaaaaat taacattact
    13921 tcaaaataat ttatatgtaa ttatatttaa atatttttat tgtatttctt ccataaagat
    13981 gtcctgctta ttccaagaac ttgtgcaact tcatttttag aaagtccctg agcaaaaagc
    14041 atacttatta ttttttcttc aacatactta tttacttctt ttatatctat acttatctta
    14101 ccatcattta tcttacttat atttatagat tcatcttgga cttctacact tgctgtcgtt
    14161 tcagaattaa atttgtctac ttcagagtta ggaagtaatt ttttagtttt aaaatctcta
    14221 tcttgtctca atttaatttt acctgtcaca acatattttt gagctattgt ctttaactct
    14281 cttacatttc caggccagct ataattatat agcttatcca tttcatcttt agtcaaaaca
    14341 aaattttcat ctatactgtt tattccattg agaccatcat cctttaatac ttcatttaca
    14401 aaattgttaa acaaaggtat tatatcttct cttctgtctc ttaaaggagg tatatttatc
    14461 tctaaactac tcaatctata aaataagtct gctctaaatg tacccataac tattttttcg
    14521 gttaaagatt cgttcgttgc tgctataatc cttatatcca gaggtattat ataatcagaa
    14581 ccaattctca ttatttgacg ttcctctatt actcttaata gttttgtctg aatattaaag
    14641 gatagactat ttatttcatc taaaaaaaga gtccctccat gagcaagttc aaatagtcct
    14701 ctttttccac cctttctagc accagtaaat gcaccttctt catagccaaa aagttcactt
    14761 tcaagtaaat tttctgctat agtagcacaa tttatagcaa caaaaggcct atcttttctt
    14821 ttacttatat tgtgtatact atgagctata atttctttac cagacccact ttctccataa
    14881 agtaaagttg tataatcact ttttccaatt tttttagctt cttcaataaa ttctctagtt
    14941 aatttatctt taaataaaaa atcatcaaaa gtatatctag catagagacc tttttgattc
    15001 aagtcaaatc ttatttttct ttctaagttt tgtagcttgg ttatatcttg tattattcct
    15061 aaaactccat aagtactatt atcaactttt attaatgttg tcctagtatt aacaattaga
    15121 ttatttatat ttcttatctt tctatcttct acatcctctt tttcatgtaa acaatctaac
    15181 atccactcca ttttaggaaa tacatctaag atgtatttat taagtgcaca ttttctctct
    15241 actttaagca tgttttttgc actttcattg tacaaaatta tactaccatt actatctata
    15301 gcaattactc catcttttat accatcaagt atatttcgta acacttcatt attaaacttt
    15361 tcttcaccta atgtatccaa taatttttta caatattcta cagcttctct tatagattca
    15421 tcactagcag ttgcaaatac actatcaatt ccatattgcc ttgcaaaaga acatgccaaa
    15481 cctcctccta cgattacaac ttcatctttt tggtctatat attttacaac tttacttctt
    15541 atctcatact tagattcaaa ccattcttca gttatttcag tacttatgac atttctccag
    15601 ccaacatagt caaaagaaac ttcattgtct ccaagaatca atactacttt tttagaatat
    15661 ttctttgcta tttctattgc tcttaaaagg tcagttgact tcatattcat tggtataaca
    15721 ggtacattta ctgtatctat tactaaacta taacctccac ctctaccaat tatagcttgg
    15781 gcaccttttt caacaagtat acgaccttga ttttccatta agtctaggtt aagtatgtcg
    15841 attattatag ttccattttc tacatcttct ctatataatt cttctattct ttcttttaat
    15901 tcaatatcag aggctataat tcctattttt tttcgcaaca aaatcacctc aattttaaat
    15961 tataatgtat tgatttctac ctgctttttt tgatttatat aggttcttat ctgcatcttc
    16021 aattaatatt tcaacatctt ttctactacg acatcttttt atacttactc cagcacttat
    16081 agttatatag ttttttattt tagaatatat atgttcaata ccctcaaatt caagaagttt
    16141 gaaaactctt ttaatatata attctatatt atcaatctct tcaacaccga ttgattctat
    16201 agaatctact agtattaaaa tttcttctcc cccatatctg attatatgtt cggtaatatc
    16261 tataaataca cttcttataa tatcagttac cttaactata actttatctc ctgctagatg
    16321 accataatta tcattataac ttttaaaaca atctatatcg actagtattg caaccatatt
    16381 tttgtctctg gttccattaa ataaatccaa ctgctgttcc aaatatcttc tattatatag
    16441 tttagtaagt ccatctttta aaatatcatt ttctaatttc ttattatcat ccactagtaa
    16501 tcttaaactc tcttgttttt gtctgagttc atattgtttg tgaattgctt gagatgtttt
    16561 ataggaatta tttttttccc acctatcaga ataccaatcc atacttttat aatattctat
    16621 tgccagttta aaatcttttt ttagctcata tccatttgct attagcccat aaaatataga
    16681 tatttttcta agattcaatg aactcttttt aactaaattt aaacctttta tataacaact
    16741 tataccttca tctatattac caaattttat atataaatct ccatacaact tatatatgta
    16801 atctagttta gaattatata taaaaacatc gccaaaactt ttatatatat tttttgataa
    16861 aattaaatag gtatttacct tttcaaaact acaattatct ttccttaact caatttcagc
    16921 tgaatataaa aatataaatg aatataaata atccttatat acaccttcaa caactttcat
    16981 taattttata gtctttaata aaataacttc tgcttcttta ttcatatctt cttttaaata
    17041 tgcccatata aggtctatct ttatagacac tctttcagtt actgatattg agttcttact
    17101 gtgcgcaaca tctaatacat tatttatgta ttttatagct tctacattat ttccactctc
    17161 taaataacac aaacttatta tacatttaca aaaagcctct atagaatata aattattttc
    17221 ttgagccagt tttagacatt caattaggta ctccatactt tttataaagt tattaaataa
    17281 atatagataa actctcccaa atatataatt tgccctactt acaagagctt tattttttaa
    17341 agttttaaaa aaagacactt cttctactaa agctattaca tccgttttgg tctgatataa
    17401 agcacttatt tctacacata aactcatatt taacaagact agcaactcat ttaaatgatt
    17461 ttgtcttata actttttttg ctgagaaata aaaattattt gccttatcat attttcttat
    17521 agaaatagct gataaagtaa gataaatata aattttagat attatatctg aatcttcttt
    17581 taatgacaat tttttaatat actttaatga ctctatcaaa tagttgtatg atgcttctct
    17641 atcttttttt atatagttta taaggctaat taaatataaa gtatagactc tactattatc
    17701 ttctagtttt gtatttaaaa ggtctttgtg ataatccaag atgtagttta aatctgtcaa
    17761 atttagatag aatttagtca acatatcgta ttctatcttg tttatatttc tctttaaatc
    17821 ttctattaaa ctccttttca agtaaatcac caatcctatt tcaacagtta aaaattctta
    17881 aaatcatgat aatgcaaaca tctatttcta ccactttcct ttgctttata taaagcttta
    17941 tcagcatttt caattatttc tcttatatct atactactat ttttacatgt atcaatgcca
    18001 atactaactg tcaaattatt gtttaaaaat ttctttacaa tcctacataa ttttcttcca
    18061 aatattttgc tttttttata atctttacat acagataata tcagaaattc ttctccacca
    18121 taccttatca taaacatgtc tttttttaga tattttttta ttattatagt tatattttta
    18181 agagcaatat ctccattata gtgtccataa gtatcattgt attctttaaa gtaatctaca
    18241 tctatcataa atgctgtgca atattcacta acttcttgtt tttctaaaaa atcgttcaaa
    18301 aaagttctat tatatgcact tgtcaaatgg tcaacatatt tttttttatc taaatcaagt
    18361 tttacttttc tcatgttatt tatttctgtt tctatatact catgtctata atttaaggaa
    18421 tctatataat ttctatttcg agcttttata tacatcattt ttaactcata atacatttta
    18481 aagtatttca tactcatttc ataattttga atcttttcaa aacacaaata tatattcttg
    18541 tatgctaact tcacataatt ataattttta gcatttttag atttttcaag gagtttttta
    18601 tttgtgttta aggcattgtc ataatatcca aagatataat atatctttgc ctgatgataa
    18661 attatttcta aatcatatat tgtatattct tctatatttt ttatcatatt taagatgttt
    18721 ttagctctat ctaaatagca tattgattgt tcaaaagatt tttcattact ttttgcataa
    18781 tacatagcta aacttataaa taaatcaaac ttctctactt cttttaagct ctgattttta
    18841 attttttcta gatatacttc agattttgct aaattattta ttgctacagg ataatttcta
    18901 gtctttatta atattttagt tatgttgttt gatgctctat atttttgaat tatatttaca
    18961 tttctatact ttttattgct tattacttca tttaaatatt ctatggaaca ttcataattt
    19021 tcaaatgaac attcacactc acctatcttt atattacata gtgaagatac ttgcatatcc
    19081 tttagtaaat ctgcatattt tcttgctttt aaaaaattta ctttagcaat tagagcatca
    19141 tccaaaaaca aaaaatatat tttaccaata ataaaaaaat atattttttt acagttaaaa
    19201 tcgttaattt cttttatctt tatatacaat gtttctattt ctttaattat tacagaagat
    19261 tctatacact tacttgcctt aatgtaaata agttgtgatt taaaaataat ttcttcaatt
    19321 agaaaattat tttcatcaca aataagatta aatttatcca tatataaatt tgccttattt
    19381 acatcttcat tttttaaact taaaatagct atttgtgaat aaaatcgtgc taaaaattta
    19441 taatctttgg gtaagcattt atcaatatat ttacaggaaa tcaaaatata ctctttcatt
    19501 ttttcactaa acccttgaat accatataat aaagctagca aaaaatttga ttttaataac
    19561 attaaactat tttgttcagt tttatagcaa tcaattaaat tctttactac accaatttta
    19621 ttttcaacaa aatcgttatt agtcaataat ctttcattca aggttagttt aaacattgaa
    19681 tctaaaattg tatcatctat ctcttccaaa tatttactat atattgtaac tcacctccga
    19741 cttacattat ctcataaatt tagtaatttt ccatactatt tttgaaaaaa attgatgtct
    19801 caatttagaa atttctctta aattaagaca tactttacac taaactatac aattttctat
    19861 ctgaactata taatcctgac aattttcaca aattatcaca cttacaatat aactattatc
    19921 aactttattt gcccttgata gtttattaaa agatagtcct ttataatcaa cagatatatt
    19981 gcttattaca tattctccat ctttactgaa aatataaaag tgatattcta aaaaaggaaa
    20041 gaattttttc ttttctttta ctccttctaa acataatgga catgcttctt gataatattc
    20101 tacatcaaaa tcaacttctt ctgcttcatt aagtatatca attatttttg aaatacttac
    20161 tccttgaact ggattttctt catcatttat taaagcacta cagttctcct cttttaataa
    20221 atattcctta tcatcatata taaacttgta taaactcata ttatatcctc cttataatta
    20281 ttaatctcca agttattcta ccacttaaat aaagttaata aaagtaattg tttataatct
    20341 ttataattaa gttatgtata catatattcc tatacactat cttaattaat gattttaaaa
    20401 tccaagttta cactttgaac atccagtttc ccaaaatcta ttgtcaaaac tcactttagt
    20461 tattaatata aggatataaa tatataactg catagatgtt acacacttaa ctatttaata
    20521 tgatacgatt tagtatctaa atttatatat tgtatatagg gggagatata tatgtataaa
    20581 gataaaagtg atgaatgtat acacttaatg actgcataca tcgatagtat aagtggatat
    20641 tattcattta ttgacacaca attagaagat tttatggtga aatatggtga aaacattgtt
    20701 gattcaaatt tacacagtat aatgatgttg ctttgtaaat ggggattatc ttagcatttt
    20761 aagaaacttt tttgtatatt gtattctata ttatttattc attaataaaa aaagattgac
    20821 ataaacttaa aagctatata tagatttctt taaaaatcta tatatagctt ttttaatttt
    20881 ttcaaaatgt atacttaaat aagttagttt tttttcaaaa tttgactatc taatatgata
    20941 taatttaact atctacaaca ataaaaaata tctaatatgt attatctagt ttagctcatc
    21001 ataataacat ccctatattt acaattaaga tattttcaat atagtaatac tcaattttaa
    21061 tattataaaa aggagagatt ttgtatgaat tacaatgact tactaaaatc agctagagag
    21121 aactttaatg gaacatgtaa agtatgtaaa atttgtaatg gattagcttg tgctggagat
    21181 gttcctggta tgggtggtaa aggaagtggt tcgtctttca ttgaaaatag aaaaagtcta
    21241 gaaaaaataa agataaatat gagagttata cataatgttt caaagccaga tacatccata
    21301 gaattatttg gtagaaaaat gagttctcct atattcgctg cacctgtatc aggtactcta
    21361 ttgaacatgg gtggtaaagt ttccgaaaaa gaatacatag agcctgttgt tagaggttgt
    21421 tctaattctg gaatttatgc tatggttggc gatactaatg tagatacttt tttactggat
    21481 aatttagatg tgttgaaaga taatagtgga aatggaattg tatttataaa gccttggaat
    21541 aattcaaaga taatagaaaa aattagattg tctgaagaag caggtgcttt tgcagttggt
    21601 gtagaccttg atgcttgtgg acttattaat aatcaatttc aagaaaatcc tttttctcct
    21661 aagacaattg atgagattag agaattggtt gaatctacta aattaccttt tattataaaa
    21721 ggaattatga ctgtagatga tgctttgatg gctgtagagt ctggtgctag tgccattatt
    21781 gtttcaaatc atggtggaag agtacttgat tatactcctg gtacttgtga ggtacttcca
    21841 gatatagcta agtctgtaaa gggaaagata acaatacttg ttgatggtgg agttaggact
    21901 ggtgttgatg tagttaagat gcttggattg ggtgctgatg ctgttttgat gggaagacct
    21961 tttgttactg cttcttttgg cggtggtctt gatggtgtgg agttttttat agagaaggtt
    22021 aggaatgagt tatgtgagac tatgattttg actggttgtc aaaatgttaa ggatatagat
    22081 ggtagagtta tatggaattt attgtaaaat atttctagac tctaagatac tgattaatat
    22141 attctatata aaaaagttgt cgccctattt cttagtgcga caacctcttt tctaataacg
    22201 ctctccgaca gcttgccaag tggcttttcc aacaacacca tcttttgtta caccaagtct
    22261 tccttgaagt atttttactt gattatatgt agcaggtcca aatttactat ctggatcaat
    22321 atcagaacca tttatttgtt gacataaaag ttgtactaaa tgcac
//
